26395-06-2 Usage
Uses
Used in Pharmaceutical Industry:
5-methyl-2-oxo-hexanoic acid is used as a reagent for the preparation of Cephalotaxus ester alkaloids, which are a class of natural products with significant biological activities. These alkaloids have been found to possess various pharmacological properties, including anti-cancer, anti-inflammatory, and anti-viral effects. The use of 5-methyl-2-oxo-hexanoic acid in their synthesis allows for the development of new therapeutic agents with potential applications in the treatment of various diseases.
Used in Chemical Synthesis:
In the field of organic chemistry, 5-methyl-2-oxo-hexanoic acid can be utilized as a building block for the synthesis of more complex molecules. Its unique structure, featuring both a ketone and a methyl group, makes it a versatile starting material for the creation of a wide range of compounds with diverse applications, such as pharmaceuticals, agrochemicals, and specialty chemicals.
Used in Research and Development:
5-methyl-2-oxo-hexanoic acid can also be employed as a research tool in the study of various chemical reactions and mechanisms. Its reactivity and structural features make it an interesting candidate for exploring new synthetic routes, reaction conditions, and catalysts. This can lead to the discovery of novel chemical processes and the development of more efficient and environmentally friendly synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 26395-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,3,9 and 5 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 26395-06:
(7*2)+(6*6)+(5*3)+(4*9)+(3*5)+(2*0)+(1*6)=122
122 % 10 = 2
So 26395-06-2 is a valid CAS Registry Number.
26395-06-2Relevant academic research and scientific papers
Process for preparing alkyl α-keto-carboxylic acids from alkyl halides
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, (2008/06/13)
A process for the production of an alkyl α-keto-carboxylic acid of the general formula: STR1 wherein: R is a linear or branched alkyl radical having from 1 to about 20 carbon atoms which comprises reacting an alkyl halide of the formula: where R is as defined above and X represents halogen, in a liquid solvent medium, with carbon monoxide at elevated temperature and pressure in the presence of a catalytic amount of a metal carbonyl compound and an alkali metal inorganic base or an alkaline earth metal inorganic base. Optionally, small amounts of LiI and/or bis(1,2-diphenylphosphino)ethane may be present in the reaction as co-catalysts.
Synthesis of antitumor alkaloid deoxyharringtonine and its precursor 3'-0-(5-methyl-2-oxohexanoyl)-cephalotaxine
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, (2008/06/13)
The alkaloid deoxyharringtonine and its precursor 3'-O-(5-methyl-2-oxohexanoyl)-cephalotaxine were synthesized according to the following preferred series of reactions: Ethyl t-butyl oxalate + 1-lithio-3-methylbut-1-yne → t-butyl 5-methyl-2-oxohex-3-ynoate → t-butyl 5-methyl-2-oxohexanoate -trifluoroacetic acid 5-methyl-2-oxohexanoic acid (COCl)2 5-methyl-2-oxohexanoyl chloride cephalotaxine 3'-O-(5-methyl-2-oxohexanoyl)-cephalotaxine lithio methyl acetate deoxyharringtonine.
