264147-99-1

Upstream product

• 264147-87-7 (E)-1-benzyloxy-3-(R)-[2-(1,3-dimethyl-2-oxo-4-(R)-5-(R)-[octahydro-2λ⁵-benzo[1.3.2]diazaphosphol-2-yl)vinyl]aziridine]-2-(R)-carboxylic acid tert-butyl ester 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 264147-90-2 1-benzyloxy-3-(S)-hydroxymethylaziridine-2-(R)-carboxylic acid tert-butyl ester 

Downstream Products

• 264147-94-6 Acetic acid (2R,3S)-1-benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-aziridin-2-ylmethyl ester 
• 264147-93-5 [(2R,3S)-1-Benzyloxy-3-(tert-butyl-dimethyl-silanyloxymethyl)-aziridin-2-yl]-methanol 

Relevant academic research and scientific papers

The synthesis of enantiomerically pure disubstituted aziridines and N- alkoxy aziridines

The addition of a chloroallyl phosphonamide anion to oximes has allowed the preparation of a variety of cis-disubstituted N-alkoxy aziridines in enantiomerically pure form. Oxidative cleavage of the chiral auxiliary followed by derivatization of the products has allowed the preparation of enantiopure N-alkoxy aziridines. (C) 2000 Elsevier Science Ltd.