264197-90-2Relevant articles and documents
Synthesis and biological evaluation of integrin antagonists containing trans- and cis-2,5-disubstituted THF rings
Osterkamp, Frank,Ziemer, Burkhard,Koert, Ulrich,Wiesner, Matthias,Raddatz, Peter,Goodman, Simon L.
, p. 666 - 683 (2007/10/03)
The synthesis of a series of RGD mimetics is described. All compounds consist of a central 2,5-disubstituted tetrahydrofuran core, a variable linker to a guanidino group, and a β-amino alanine unit to mimic the carboxylic acid. Three types of linkers were