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3-Indoxyl sulfate potassium salt is an uremic toxin that acts as a potent endogenous agonist for the human aryl hydrocarbon receptor (AHR). It is a white to off-white crystalline powder and is considered a sensitive and early biomarker of nephrotoxicity.

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  • 2642-37-7 Structure
  • Basic information

    1. Product Name: 3-INDOXYL SULFATE POTASSIUM SALT
    2. Synonyms: POTASSIUM 1H-INDOL-3-YL SULFATE;POTASSIUM 3-INDOXYL SULFATE;Y(TM)-SULFATE K;Y(TM)-SULFATE, POTASSIUM SALT;URINARY INDICAN;URINARY INDICAN POTASSIUM SALT;3-indoxylsulfuricacid,potassiumsalt;indol-3-ol,hydrogensulfate(ester),potassiumsalt
    3. CAS NO:2642-37-7
    4. Molecular Formula: C8H6NO4S*K
    5. Molecular Weight: 251.3
    6. EINECS: 220-145-5
    7. Product Categories: Indoles and derivatives;Agonists;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Sulfur & Selenium Compounds;Building Blocks;C7 to C9;Chemical Synthesis;Heterocyclic Building Blocks;Indoles
    8. Mol File: 2642-37-7.mol
  • Chemical Properties

    1. Melting Point: 165 °C (dec.)(lit.)
    2. Boiling Point: °Cat760mmHg
    3. Flash Point: °C
    4. Appearance: light yellow/
    5. Density: g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: DMSO (Sparingly), Methanol (Slightly)
    9. Sensitive: Light Sensitive
    10. Stability: Hygroscopic
    11. BRN: 3921324
    12. CAS DataBase Reference: 3-INDOXYL SULFATE POTASSIUM SALT(CAS DataBase Reference)
    13. NIST Chemistry Reference: 3-INDOXYL SULFATE POTASSIUM SALT(2642-37-7)
    14. EPA Substance Registry System: 3-INDOXYL SULFATE POTASSIUM SALT(2642-37-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 22-24/25
    4. WGK Germany: 3
    5. RTECS: NM3200000
    6. F: 8-10-23
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 2642-37-7(Hazardous Substances Data)

2642-37-7 Usage

Uses

Used in Pharmaceutical Industry:
3-Indoxyl sulfate potassium salt is used as a pharmaceutical agent for the treatment of chronic kidney disease and related conditions. Its ability to act as an AHR agonist makes it a potential therapeutic target for modulating the AHR pathway, which plays a role in various physiological and pathological processes.
Used in Research Applications:
3-Indoxyl sulfate potassium salt is used as a research tool for studying the role of AHR in various biological processes and diseases. It helps researchers understand the molecular mechanisms underlying the AHR pathway and its implications in nephrotoxicity and other conditions.
Used in Diagnostic Applications:
3-Indoxyl sulfate potassium salt is used as a biomarker for the early detection of nephrotoxicity, allowing for timely intervention and management of kidney-related disorders. Its sensitivity as a biomarker makes it a valuable tool in the diagnosis and monitoring of kidney function.

Check Digit Verification of cas no

The CAS Registry Mumber 2642-37-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,6,4 and 2 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2642-37:
(6*2)+(5*6)+(4*4)+(3*2)+(2*3)+(1*7)=77
77 % 10 = 7
So 2642-37-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1

2642-37-7 Well-known Company Product Price

  • Brand
  • (Code)Product description
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  • Aldrich

  • (I3875)  Indoxylsulfatepotassiumsalt  

  • 2642-37-7

  • I3875-250MG

  • 888.03CNY

  • Detail
  • Aldrich

  • (I3875)  Indoxylsulfatepotassiumsalt  

  • 2642-37-7

  • I3875-1G

  • 1,639.17CNY

  • Detail

2642-37-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name potassium,1H-indol-3-yl sulfate

1.2 Other means of identification

Product number -
Other names 3-Indoxyl sulfate potassium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2642-37-7 SDS

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