2642-43-5

Basic information

• Product Name: thymidine 3'-monophosphate ammonium salt hydrate
• Synonyms: thymidine 3'-monophosphate ammonium salt hydrate;3'-thymidylic acid;Thymidine 3μ-monophosphate hydrate ammonium salt;3'-TMP;Thymidine 3'-phosphate;Thymidine 3'-phosphoric acid;Thymidine-3'-phosphoric acid;thymidine 3'-monophosphate
• CAS NO: 2642-43-5
• Molecular Formula: C₁₀H₁₅N₂O₈P
• Molecular Weight: 322.21
• Product Categories: Biochemicals and Reagents;Nucleosides, Nucleotides, Oligonucleotides;Nucleotides
• Mol File: 2642-43-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.654g/cm³
• Storage Temp.: −20°C
• PKA: 1.83±0.10(Predicted)
• CAS DataBase Reference: thymidine 3'-monophosphate ammonium salt hydrate(CAS DataBase Reference)
• NIST Chemistry Reference: thymidine 3'-monophosphate ammonium salt hydrate(2642-43-5)
• EPA Substance Registry System: thymidine 3'-monophosphate ammonium salt hydrate(2642-43-5)

Safety Data

• Hazardous Substances Data: 2642-43-5(Hazardous Substances Data)

Usage

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside 3'-monophosphate having thymine as the nucleobase.

Upstream product

• 68030-66-0 deoxythymidylyl-(5'->3')-deoxythymidine-(Pⁱⁿ->N)-phenylalanine 
• 68030-67-1 deoxythymidylyl-(3'->N)-phenylalanine 
• 56883-49-9 Thiophosphoric acid O-[(2R,3S,5R)-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl] ester S-phenyl ester 
• 538-37-4 dibenzyl phosphochloridate 
• 50-89-5 thymidine 

Downstream Products

• 2476-56-4 5'-d(TpTp)-3' 
• 50-89-5 thymidine 

Relevant articles and documents

A NEW SOLID PHASE APPROACH FOR RAPID SYNTHESES OF OLIGONUCLEOTIDES BEARING A 3'-TERMINAL PHOSPHATE GROUP

Synthesis of pentanucleotide ApTpCpTpTp containing a 3'-terminal phosphomonoester group was accomplished with the help of the new phosphate-solid phase link 2-(4-carboxyphenylmercapto)ethanol; a similar molecule, 2-benzylsulfonylethanol, revealed interesting features as a temporary 3'-phosphate protecting group.

Synthesis and Properties of Thymidine Derivatives Bearing the (PhS)2P(O) and (PhS)(PhNH)P(O) groups

A new phosphorylating agent, cyclohexylammonium S-phenyl phosphoranilidothioate (2), was prepared in high yield.In this paper, the highly selective deprotection of the phenylthio or anilino group from thymidine 3',5'-diphosphate derivatives masked with th