409127-32-8

Basic information

• Product Name: Methyl 2,6-dichloro-4-cyanobenzoate
• Synonyms: Methyl 2,6-dichloro-4-cyanobenzoate;2，6-dichloro-4-cyanobenzoic acid
• CAS NO: 409127-32-8
• Molecular Formula: C₉H₅Cl₂NO₂
• Molecular Weight: 230.049
• Mol File: 409127-32-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 319.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.45
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 2,6-dichloro-4-cyanobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2,6-dichloro-4-cyanobenzoate(409127-32-8)
• EPA Substance Registry System: Methyl 2,6-dichloro-4-cyanobenzoate(409127-32-8)

Safety Data

• Hazardous Substances Data: 409127-32-8(Hazardous Substances Data)

Usage

General Description

Methyl 2,6-dichloro-4-cyanobenzoate is a chemical compound with the molecular formula C9H5Cl2NO2. It is a white solid that is used as an intermediate in the production of various pharmaceuticals and agrochemicals. Methyl 2,6-dichloro-4-cyanobenzoate is commonly used as an intermediate in the synthesis of Pyridaben, a widely used acaricide that is effective against a variety of mites and ticks. Methyl 2,6-dichloro-4-cyanobenzoate is also used in the production of other chemicals and is known for its high stability and low toxicity. It is important to handle this compound with care and follow safety guidelines when working with it in laboratory settings.

Upstream product

• 409127-31-7 methyl 4-carbamoyl-2,6-dichlorobenzoate 
• 264272-64-2 2,6-dichlorobenzene-1,4-dicarboxylic acid,1-methyl ester 
• 264276-14-4 dimethyl 2,6-dichlorobenzene-1,4-dicarboxylate 
• 1258298-04-2 2-amino-3,5-dichloro-4-(carbomethoxy)benzoic acid methyl ester 
• 5372-81-6 dimethyl aminoterephthalate 

Downstream Products

• 1258298-05-3 2,6-dichloro-4-cyanobenzoic acid 
• 1258295-23-6 2,6-dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)-4-(4H-1,2,4-triazol-3-yl)benzamide 
• 1438897-33-6 2,6-dichloro-N₁-(2-(cyclopropanecarboxamido)pyridin-4-yl)terephthalamide 
• 1258294-28-8 2,6-dichloro-4-cyano-N-(2-(cyclopropanecarboxamido)-pyridin-4-yl)benzamide 
• 1258294-31-3 2,6-dichloro-4-cyano-N-(2-(1R,2R)-(2-fluorocyclopropanecarboxamido)pyridin-4-yl)benzamide 
• 1258294-30-2 2,6-dichloro-4-cyano-N-(2-((1S,2S)-2-fluorocyclopropanecarboxamido)pyridin-4-yl)benzamide 
• 1258298-06-4 2,6-dichloro-4-cyanobenzoyl chloride 
• 1258298-07-5 N-(2-bromopyridin-4-yl)-2,6-dichloro-4-cyanobenzamide 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A′ B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.

HETEROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A' B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family.

New phenylalanine derivatives

Specific phenylalanine derivatives or pharmaceutically acceptable. salts thereof have an antagonistic effect on the α4 integrins and, therefore, are usable as therapeutic agents or preventive agents for diseases in which α4 integrin-depending adhesion process participates in the pathology, such as inflammatory diseases, rheumatoid arthritis, inflammatory bowel diseases, systemic lupus erythematosus, multiple sclerosis, Sj?gren's syndrome, asthma, psoriasis, allergy, diabetes, cardiovascular diseases, arterial sclerosis, restenosis, tumor proliferation, tumor metastasis and transplantation rejection.