26437-22-9 Usage
General Description
4-Amino-2-fluorobutanoic acid hydrochloride is a chemical compound with the molecular formula C4H8FNO2.HCl. It is a derivative of the neurotransmitter γ-aminobutyric acid (GABA), and it is commonly used in research and as a precursor for the synthesis of pharmaceuticals. 4-aMino-2-fluorobutanoic acid hydrochloride is a white crystalline powder that is soluble in water and has a high melting point. It has been studied for its potential applications in the treatment of anxiety and other neurological disorders, as well as for its role in the development of new drugs targeting the GABA system. Additionally, 4-Amino-2-fluorobutanoic acid hydrochloride has been investigated for its potential use as a building block in the synthesis of novel organic molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 26437-22-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,4,3 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 26437-22:
(7*2)+(6*6)+(5*4)+(4*3)+(3*7)+(2*2)+(1*2)=109
109 % 10 = 9
So 26437-22-9 is a valid CAS Registry Number.
26437-22-9Relevant articles and documents
Design, Synthesis, and Biological Evaluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker
Ma, Huan,Chen, Gang,Wang, Tao,Li, Qingeng,Liu, Yan
, p. 363 - 369 (2016)
The synthesis and preliminary evaluation of derivatives of docetaxel with novel amino acid as a linker named as LK-193?LK-196 was described. The C2′-modified compound LK-196 behaves as a prodrug; that is, docetaxel is generated upon exposure to human plasma. The compound was also found to have greatly improved water solubility. The pharmacodynamic results showed LK-196 had the self-evident inhibitory effect on tumor growth in vivo, which is a promising candidate for further biological evaluation.
DNA sequence selectivity of hairpin polyamide turn units
Farkas, Michelle E.,Li, Benjamin C.,Dose, Christian,Dervan, Peter B.
supporting information; experimental part, p. 3919 - 3923 (2010/03/02)
A class of hairpin polyamides linked by 3,4-diaminobutyric acid, resulting in a β-amine residue at the turn unit, showed improved binding affinities relative to their α-amino-γ-turn analogs for particular sequences. We incorporated β-amino-γ-turns in six-
