26452-99-3

Basic information

• Product Name: 2,3-DIHYDRO-1H-INDEN-1-YLACETONITRILE
• Synonyms: 2,3-DIHYDRO-1H-INDEN-1-YLACETONITRILE
• CAS NO: 26452-99-3
• Molecular Formula: C11H11N
• Molecular Weight: 157.21
• Mol File: 26452-99-3.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,3-DIHYDRO-1H-INDEN-1-YLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1H-INDEN-1-YLACETONITRILE(26452-99-3)
• EPA Substance Registry System: 2,3-DIHYDRO-1H-INDEN-1-YLACETONITRILE(26452-99-3)

Safety Data

• Hazardous Substances Data: 26452-99-3(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1H-inden-1-ylacetonitrile is a chemical compound with the molecular formula C11H11N. It is a nitrile derivative of indene, which is a bicyclic aromatic hydrocarbon. 2,3-DIHYDRO-1H-INDEN-1-YLACETONITRILE is commonly used in organic synthesis and as an intermediate in the production of other chemicals. 2,3-Dihydro-1H-inden-1-ylacetonitrile is also a key building block in the pharmaceutical industry, where it is used in the synthesis of various drugs and pharmaceutical products. It is important to handle this compound with caution as it can be toxic and may pose risks to human health and the environment if not properly managed.

Upstream product

• 52957-55-8 indan-1-acetic acid chloride 
• 52957-54-7 indan-1-yl-malonic acid diethyl ester 
• 7316-61-2 3,4-benzo-6,6-dichlorobicyclo<3.2.0>heptan-7-one 
• 38425-65-9 indan-1-ylacetic acid 
• 31996-70-0 2,2a,7,7a-tetrahydro-cyclobuta[a]inden-1-one 
• 156963-20-1 N-(2,2a,7,7a-tetrahydro-1H-cyclobut<α>indene-1-ylidene)-benzenesulfenamide 
• 2537-48-6 diethyl 1-cyanomethylphosphonate 
• 83-33-0 inden-1-one 
• 131251-80-4 C₁₇H₁₅NS 
• 52957-56-9 indan-1-yl-acetic acid amide 
• 35275-62-8 1-chloroindane 
• 95-13-6 1-indene 
• 154592-55-9 2,2a,7,7a-tetrahydro-cyclobuta[a]inden-1-one oxime 

Downstream Products

• 4458-36-0 1-(2-aminoethylindan) 

Relevant articles and documents

NOVEL TRPV3 MODULATORS

Disclosed herein are modulators of TRPV3 of formula (I) wherein G1, X1, X2, X3, X4, X5, G2, Z1, Ra, Rb, u, and p are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also presented.

An unprecedented radical reaction of benzotriazole derivatives. A new efficient method for the generation of iminyl radicals

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Iminyl radicals by stannane mediated cleavage of oxime esters

Despite the explosive growth in the use of radical reactions which has swept organic synthesis in the past few years, nitrogen centred radicals and iminyls in particular have not yet attracted the attention they deserve This can be traced to a large extent to a lack of convenient and mild methods for generating such species. As part of a general study of the reactivity and synthetic potential of iminyls, we recently showed that the reaction of sulfenimines with tributystannane or the Barton decarboxylation of O-carboxymethyl oximes represented useful routes to these intermediates. Another promising approach, still in its preliminary stages however, involved the reduction of oxime esters with nickel powder in acetic acid. in this Letter, we describe yet another method based on the cleavage of oxime benzoates with tin centered radicals.