264603-22-7

Upstream product

• 123-38-6 propionaldehyde 
• 264603-21-6 2-[(4R)-5-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-4-hydroxy-pentyl]-6-methyl-pyran-4-one 
• 58931-16-1 (R)-1-benzyloxypent-4-en-2-ol 
• 14618-80-5 (R)-benzyl glycidol 
• 264603-33-0 2-[(4R)-5-benzyloxy-2-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-pentyl]-6-methyl-pyran-4-one 
• 264603-20-5 2-[(4R)-5-benzyloxy-2-hydroxy-4-(4-methoxy-benzyloxy)-pentyl]-6-methyl-pyran-4-one 
• 264603-19-2 (2R)-1-benzyloxy-2-(4-methoxy-benzyloxy)-pent-4-ene 
• 264603-16-9 (3R)-4-benzyloxy-3-(4-methoxy-benzyloxy)-butyraldehyde 

Downstream Products

• 264603-23-8 (6R,8R,10S)-8-benzyloxymethyl-10-(tert-butyl-dimethyl-silanyloxy)-2-(2-hydroxy-butyl)-1,7-dioxa-spiro[5.5]undec-2-en-4-one 
• 264603-34-1 (6R,8R,10R)-8-benzyloxymethyl-10-(tert-butyl-dimethyl-silanyloxy)-2-(2-hydroxy-butyl)-1,7-dioxa-spiro[5.5]undec-2-en-4-one 

Relevant academic research and scientific papers

Synthesis of the C16-C28 spiroketal Subunit of spongistatin 1 (altohyrtin A): The pyrone approach

(Equation presented) The synthesis of the CD spiroketal fragment of spongistatin 1 (altohyrtin A) has been accomplished utilizing the addition of a metalated pyrone to an aldehyde and subsequent acid-catalyzed spirocyclization. A stereoselective hydrogena