264608-40-4

Basic information

• Product Name: 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(2-pyridinyl)-
• CAS NO: 264608-40-4
• Molecular Formula: C12H16N2O2
• Molecular Weight: 220.271
• Mol File: 264608-40-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(2-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(2-pyridinyl)-(264608-40-4)
• EPA Substance Registry System: 1,4-Dioxa-8-azaspiro[4.5]decane, 8-(2-pyridinyl)-(264608-40-4)

Safety Data

• Hazardous Substances Data: 264608-40-4(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 177-11-7 4,4-ethylenedioxy-piperidine 

Downstream Products

• 1261144-87-9 7-phenyl-8-(pyridin-2-yl)-1,4-dioxa-8-azaspiro[4.5]decane 
• 264608-41-5 1-(pyridin-2-yl)piperidin-4-one 
• 199117-78-7 N-(2-pyridinyl)-4-hydroxypiperidine 

Relevant articles and documents

Palladium-catalysed amination of halopyridines on a KF-alumina surface

Palladium-catalysed C-N hetero cross-coupling reactions between bromopyridines and amines (both primary and secondary) can be efficiently performed on a KF-alumina (basic) surface, thus negating the use of strong bases such as sodium tert-butoxide. The reaction conditions are optimised with reference to catalytic systems, solvents and the surface.