264617-43-8

Basic information

• Product Name: 2-(3,4-DIMETHOXYBENZYL)-6-HYDROXYBENZENECARBONITRILE
• Synonyms: 2-(3,4-DIMETHOXYBENZYL)-6-HYDROXYBENZENECARBONITRILE;2-[(3,4-dimethoxyphenyl)methyl]-6-hydroxybenzonitrile
• CAS NO: 264617-43-8
• Molecular Formula: C16H15NO3
• Molecular Weight: 269.3
• Mol File: 264617-43-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,4-DIMETHOXYBENZYL)-6-HYDROXYBENZENECARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DIMETHOXYBENZYL)-6-HYDROXYBENZENECARBONITRILE(264617-43-8)
• EPA Substance Registry System: 2-(3,4-DIMETHOXYBENZYL)-6-HYDROXYBENZENECARBONITRILE(264617-43-8)

Safety Data

• Hazardous Substances Data: 264617-43-8(Hazardous Substances Data)

Upstream product

• 95-56-7 2-hydroxybromobenzene 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 591-20-8 3-Bromophenol 

Relevant articles and documents

The synthesis of 2-arylmethyl-6-hydroxybenzenecarbonitriles from the base-mediated aryne reaction of bromophenols with arylacetonitriles

A facile one-step synthesis of 2-arylmethyl-6-hydroxybenzenecarbonitriles from readily available arylacetonitriles is described. The substitution pattern was verified by X-ray diffractometric analysis of 2-benzyl-6-hydroxybenzonitrile. An explanation of the addition to and reactivity of the 2,3-didehydrophenoxide intermediate, which is supported by DFT calculations, is presented.