26462-85-1

Upstream product

• 26462-82-8 Toluene-4-sulfonic acid (S)-2-((S)-4-methyl-cyclohex-3-enyl)-propyl ester 
• 17844-06-3 2-<4-Carboxy-Δ³-cyclohexenyl)-6-methyl-heptanol-(4) 
• 26462-74-8 (-)-Juvabion 
• 262290-95-9 (3S)-3-[(1S)-4-Methylcyclohex-3-enyl]butanol dinitrobenzoate ester 
• 262290-99-3 (1S)-5-[(1S)-3-Hydroxy-1,5-dimethylhexyl]-2-methylenecyclohexanol 
• 262290-98-2 (2S)-2-[(1S)-4-Methylcyclohex-3-enyl]-6-methylheptan-4-ol 
• 262290-93-7 (S)-3-((S)-4-Methyl-cyclohex-3-enyl)-butan-1-ol 
• 156406-00-7 (E)-3-([1S)-4-Methylcyclohex-3-enyl]but-2-enal 
• 138117-27-8 (S)-3-((S)-4-methylcyclohex-3-en-1-yl)butanal 
• 5989-54-8 (-)-(S)-limonene 
• 17844-04-1 2-(4-Cyan-4-hydroxy-cyclohexyl)-6-methyl-4-acetoxy-heptan 
• 17844-03-0 2-(4-Oxo-cyclohexyl)-4-acetoxy-6-methyl-heptan 
• 17844-05-2 2-<4-Cyan-Δ³-cyclohexenyl)-4-acetoxy-6-methyl-heptan 
• 58493-52-0 Methyl-4-(3-hydroxy-2.6-dimethylhexyl)cyclohex-1-en-carboxylat 

Downstream Products

• 17015-46-2 methyl (+/-)-rel-(4R)-4-[(1R)-1,5-dimethyl-3-oxoethyl]cyclohex-1-enecarboxylate 
• 16981-74-1 (+/-)-erythro-juvabione 

Relevant academic research and scientific papers

Baker's yeast mediated enantioselective synthesis of the bisabolene sesquiterpenes (+)-epijuvabione and (-)-juvabione

Fermenting baker's yeast converts the unsaturated aldehydes 7 and 11 into the saturated alcohols 8 and 12, respectively. The microbial saturation of the double bond proceeds in high chemical yields and the stereoselectivity of the reduction is strongly influenced by the E:Z ratio of the substrate. Enantiopure 8 and 12 are chiral building blocks for the synthesis of bisabolene sesquiterpenes and their usefulness is shown in the preparation of (+)-epijuvabione 1 and (-)-juvabione 3.