2648-59-1Relevant academic research and scientific papers
Conversion of alkynes into α,α-dichloro ketones and α,α-dichlorodimethyl ketals using trichloroisocyanuric acid
Hiegel, Gene A.,Bayne, Christopher D.,Ridley, Brendt
, p. 1997 - 2002 (2003)
Trichloroisocyanuric acid reacts with alkynes in the presence of water in acetone or acetonitrile to form α,α-dichloro ketones and in methanol to form α,α-dichlorodimethyl ketals.
3-CYCLYL-5-(NITROGEN-CONTAINING 5-MEMBERED RING) METHYL-OXAZOLIDINONE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS
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Page/Page column 59, (2008/06/13)
Compounds of the formula (I), or a pharmaceutically-acceptable salt, or an in-vivo-hydrolysable ester thereof, (I) wherein -N-HET is, for example, (Ic) or (If) wherein R1 is (1-4C)alkyl;Q is selected from, for example, Q1 (Q1) wherein R2 and R
One-pot Synthesis of α,α-Dichloroketones from Alkynes Using the N,N-Dimethylformamide/HCl/Potassium Monoperoxysulfate System
Kim, Kye Kwang,Kim, Jae Nyoung,Kim, Kyoung Mahn,Kim, Hyoung Rae,Ryu, Eung K.
, p. 603 - 604 (2007/10/02)
The reaction of alkynes with N,N-dimethylformamide (DMF)/HCl/potassium monoperoxysulfate (Oxone, Aldrich) afforded the corresponding α,α-dichloroketones in good yields.
PRODUCTION OF 1,1,1-TRIHALOGENO-2-ALKANOLS AND SOME OF THEIR PROPERTIES
Bal'on, Ya. G.,Shul'man, M. D.,Vakulenko, L. I.
, p. 1231 - 1237 (2007/10/02)
The reaction of acyclic and carbocyclic carbonyl compounds with haloforms was studied in liquid ammonia and dimethylformamide in the presence of basic catalysts (t-BuOK, KOH).As a result of the reaction 1,1,1-trihalogeno-2-alkanols were obtained.They were used for the synthesis of 1,1,1-trihalogeno-2-methoxyalkanes, 1,1-dibromoalkenes, 1,1-dichloro-2-methoxyalkenes, and alkyl mono- and dichloromethyl ketones.
