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Usage

Uses

Used in Agricultural Industry:
Phenylpyridylmethyl acetate is used as an insecticide for protecting crops from a variety of pests such as mosquitoes, flies, ants, and cockroaches. Its application helps in reducing crop damage and increasing agricultural productivity by ensuring a healthy growth environment for plants.
Used in Household Pest Control:
In household settings, Phenylpyridylmethyl acetate is used as an insect repellent to keep insects at bay, creating a more comfortable living space. Its fast-acting nature makes it an effective solution for immediate pest problems, providing quick relief from insect infestations.
Used in Formulation of Insecticides:
Phenylpyridylmethyl acetate is a key ingredient in the formulation of various insecticides and repellents. Its potent action against insects makes it a valuable component in creating effective pest control products for both commercial and domestic use.
It is crucial to handle Phenylpyridylmethyl acetate with care and adhere to safety guidelines to minimize potential harm to humans and the environment. Proper use and disposal are essential to ensure the safety and sustainability of its applications.

Upstream product

• 5005-36-7 phenyl-pyridin-2-yl-acetonitrile 
• 109-09-1 2-chloropyridine 
• 67-56-1 methanol 
• 39930-11-5 1-phenyl-1-(pyridin-2-yl)methanamine 
• 201230-82-2 carbon monoxide 
• 109-04-6 2-bromo-pyridine 
• 140-29-4 phenylacetonitrile 
• 7251-52-7 2-phenyl-2-(pyridin-2-yl)acetamide 

Downstream Products

• 113-45-1 METHYLPHENIDATE 

Relevant academic research and scientific papers

Structure-activity relationship and cardiac safety of 2-aryl-2-(pyridin-2-yl)acetamides as a new class of broad-spectrum anticonvulsants derived from Disopyramide

A series of 2-aryl-2-(pyridin-2-yl)acetamides were synthesized and screened for their anticonvulsant activity in animal models of epilepsy. The compounds were broadly active in the ‘classical’ maximal electroshock seizure (MES) and subcutaneous Metrazol (scMET) tests as well as in the 6 Hz and kindling models of pharmacoresistant seizures. Furthermore, the compounds showed good therapeutic indices between anticonvulsant activity and motor impairment. Structure-activity relationship (SAR) trends clearly showed the highest activity resides in unsubstituted phenyl derivatives or compounds having ortho- and meta- substituents on the phenyl ring. The 2-aryl-2-(pyridin-2-yl)acetamides were derived by redesign of the cardiotoxic sodium channel blocker Disopyramide (DISO). Our results show that the compounds preserve the capability of the parent compound to inhibit voltage gated sodium currents in patch-clamp experiments; however, in contrast to DISO, a representative compound from the series 1 displays high levels of cardiac safety in a panel of in vitro and in vivo experiments.

Palladium-Catalyzed Carbonylative Direct Transformation of Benzyl Amines under Additive-Free Conditions

In this communication, we developed a new procedure for the direct carbonylative transformation of benzyl amines. Using dimethyl carbonate as the solvent, methyl 2-arylacetates can be produced in good to excellent yields from the corresponding primary, secondary, and tertiary benzyl amines with palladium as the catalyst. Notably, no base or any other additive is required here. In addition, our procedure can also be applied in the preparation of methylphenidate, which is a marketing drug and used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy.

Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives

The present invention is concerned with the use of carbonylamino derivatives of the formula wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF3; R1signifies hydrogen or lower alkyl; R2and R3signify, independently from each other, hydrogen, halogen or nitro; Y signifies CH or N; n is 0-6; m is 0-2; as well as with their pharmaceutically acceptable salts for the treatment of diseases, which relate to metabotropic glutamate receptor antagonists and/or agonists.

Neuropeptide Y antagonists

The compound is a neuropeptide Y antagonist and is effective in treating feeding disorders, cardiovascular diseases and other physiological disorders.

Amide derivatives useful as Neuropeptide Y (NPY) antagonists

The compound is a neuropeptide Y antagonist and is effective in treating feeding disorders, cardiovascular diseases and other physiological disorders.