26483-64-7

Basic information

• Product Name: PHENYLPYRIDYLMETHYL ACETATE
• Synonyms: PHENYLPYRIDYLMETHYL ACETATE;Methyl 2-phenyl-2-(pyridin-2-yl)acetate;(RS)-phenyl-pyridin-2-yl-acetic acid methyl ester
• CAS NO: 26483-64-7
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Mol File: 26483-64-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: PHENYLPYRIDYLMETHYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLPYRIDYLMETHYL ACETATE(26483-64-7)
• EPA Substance Registry System: PHENYLPYRIDYLMETHYL ACETATE(26483-64-7)

Safety Data

• Hazardous Substances Data: 26483-64-7(Hazardous Substances Data)

Usage

General Description

Phenylpyridylmethyl acetate is a chemical compound that belongs to the class of pyrethroid insecticides. It is often used in the formulation of insect repellents and insecticides for both agricultural and household purposes. PHENYLPYRIDYLMETHYL ACETATE is known for its ability to effectively repel and kill insects, including mosquitoes, flies, ants, and cockroaches. It works by disrupting the nervous system of the insects, leading to paralysis and eventual death. Phenylpyridylmethyl acetate is considered a potent and fast-acting insecticide, making it a popular choice for pest control in many different settings. However, it is important to use this chemical with caution and in accordance with safety guidelines to prevent harm to humans and the environment.

Upstream product

• 5005-36-7 phenyl-pyridin-2-yl-acetonitrile 
• 109-04-6 2-bromo-pyridine 
• 67-56-1 methanol 
• 39930-11-5 1-phenyl-1-(pyridin-2-yl)methanamine 
• 201230-82-2 carbon monoxide 
• 7251-52-7 2-phenyl-2-(pyridin-2-yl)acetamide 
• 140-29-4 phenylacetonitrile 
• 109-09-1 2-chloropyridine 

Downstream Products

• 113-45-1 METHYLPHENIDATE 

Relevant articles and documents

Structure-activity relationship and cardiac safety of 2-aryl-2-(pyridin-2-yl)acetamides as a new class of broad-spectrum anticonvulsants derived from Disopyramide

A series of 2-aryl-2-(pyridin-2-yl)acetamides were synthesized and screened for their anticonvulsant activity in animal models of epilepsy. The compounds were broadly active in the ‘classical’ maximal electroshock seizure (MES) and subcutaneous Metrazol (scMET) tests as well as in the 6 Hz and kindling models of pharmacoresistant seizures. Furthermore, the compounds showed good therapeutic indices between anticonvulsant activity and motor impairment. Structure-activity relationship (SAR) trends clearly showed the highest activity resides in unsubstituted phenyl derivatives or compounds having ortho- and meta- substituents on the phenyl ring. The 2-aryl-2-(pyridin-2-yl)acetamides were derived by redesign of the cardiotoxic sodium channel blocker Disopyramide (DISO). Our results show that the compounds preserve the capability of the parent compound to inhibit voltage gated sodium currents in patch-clamp experiments; however, in contrast to DISO, a representative compound from the series 1 displays high levels of cardiac safety in a panel of in vitro and in vivo experiments.

Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives

The present invention is concerned with the use of carbonylamino derivatives of the formula wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF3; R1signifies hydrogen or lower alkyl; R2and R3signify, independently from each other, hydrogen, halogen or nitro; Y signifies CH or N; n is 0-6; m is 0-2; as well as with their pharmaceutically acceptable salts for the treatment of diseases, which relate to metabotropic glutamate receptor antagonists and/or agonists.

Amide derivatives useful as Neuropeptide Y (NPY) antagonists

The compound is a neuropeptide Y antagonist and is effective in treating feeding disorders, cardiovascular diseases and other physiological disorders.