264879-05-2

Basic information

• Product Name: 4-cyclohexylidene-2-methyl-5-(trimethylsilyl)pent-1-en-3-one
• CAS NO: 264879-05-2
• Molecular Weight: 250.456
• Mol File: 264879-05-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-cyclohexylidene-2-methyl-5-(trimethylsilyl)pent-1-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-cyclohexylidene-2-methyl-5-(trimethylsilyl)pent-1-en-3-one(264879-05-2)
• EPA Substance Registry System: 4-cyclohexylidene-2-methyl-5-(trimethylsilyl)pent-1-en-3-one(264879-05-2)

Safety Data

• Hazardous Substances Data: 264879-05-2(Hazardous Substances Data)

Upstream product

• 159531-03-0 ethyl 2-cyclohexylidene-3-(trimethylsilyl)propanoate 
• 159531-06-3 2-cyclohexylidene-3-(trimethylsilyl)propanal 
• 306326-67-0 2-cyclohexylidene-3-trimethylsilyl-1-propanol 
• 110481-61-3 3-trimethylsilyl-2-diethylphosphonopropionic acid ethyl ester 
• 306326-75-0 4-cyclohexylidene-2-methyl-5-(trimethylsilyl)pent-1-en-3-ol 

Relevant articles and documents

Nazarov cyclization of 4-cycloalkylidene-5-(trimethylsilyl)pent-1-en-3-one derivatives. Synthesis of spiro[4.5]decane, Spiro[4.4]nonane, and Their derivatives

Spiro[4.5]decane and spiro[4.4]nonane ring systems were synthesized by FeCl3-induced Nazarov cyclization of α-(trimethylsilylmethyl)divinyl ketone derivatives. It was found that the double bond position of the product is controlled by the presence/absence of α'-substituent, while trimethylsilyl group is essential to obtain the products in good yields. Spiro[4.4]nonanes having exo-methylene group underwent rearrangement to bicyclo[4.3.0]nonanes. (C) 2000 Elsevier Science Ltd.