26516-42-7

Basic information

• Product Name: Benzene, 2-iodo-1,3-dinitro-
• CAS NO: 26516-42-7
• Molecular Formula: C6H3IN2O4
• Molecular Weight: 294.005
• Mol File: 26516-42-7.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Benzene, 2-iodo-1,3-dinitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-iodo-1,3-dinitro-(26516-42-7)
• EPA Substance Registry System: Benzene, 2-iodo-1,3-dinitro-(26516-42-7)

Safety Data

• Hazardous Substances Data: 26516-42-7(Hazardous Substances Data)

Upstream product

• 609-73-4 o-nitroiodobenzene 
• 606-22-4 2,6-dinitroaniline 
• 591-50-4 iodobenzene 

Downstream Products

• 606-22-4 2,6-dinitroaniline 
• 961-68-2 N-phenyl-2,4-dinitroaniline 
• 13744-81-5 2,6-dinitro-N-phenyl-benzenamine 
• 1200462-36-7 7-[1-(2,6-dinitrophenyl)-2-methyl-propyloxy]methyl-7-deaza-2'-deoxyadenosine 
• 1200462-34-5 9-[β-D-2′-deoxyribofuranosyl]-6-chloro-7-[1-(2,6-dinitrophenyl)-2-methylpropyloxy]methyl-7-deazapurine 
• 1200461-10-4 (R/S)-1-(2,6-dinitrophenyl)-2-methyl-1-propanol 

Relevant articles and documents

Substituted Fused Heteroaromatic Tricyclic Compounds as Kinase Inhibitors and The Use Thereof

The disclosure relates to substituted fused heteroaromatic tricyclic compounds and the use thereof. Specifically, the disclosure provides compounds of the following Formula I: or a pharmaceutically acceptable salt or prodrug thereof, wherein A1

Synthesis of 5,9-Diaza[5]helicenes

A new method for the synthesis of 5,9-diaza[5]helicenes is presented using 2,3-bis(acylamino)-substituted ortho-terphenyls as precursors. Activation of the amide groups and electrophilic substitution at the ortho positions of the adjacent phenyl groups leads to the 5,9-diaza[5]helicenes. A stepwise reaction including protection of the first amino group, amide formation at the second amino group with subsequent cyclization, followed by deprotection, amide formation and cyclization at the first amino group ensures that both electrophilic substitutions take place at sufficiently activated arenes and allows for the different substituents at the diaza[5]helicenes brought in with the amide groups. The terphenyl precursors are synthesized by two Suzuki couplings of suitably substituted building blocks. Three different 5,9-diaza[5]helicenes with aliphatic, alkenyl and methoxycarbonylalkyl substituents were prepared; the latter would allow to attach further functionalities by ester or amide linkage.

Domino Carbopalladation/C-H Activation as a Quick Access to Polycyclic Frameworks

A new type of domino reaction for synthesis of heterocycles fusing the important bioactive cores, such as oxindole, indoline, and isoquinoline, is presented. Upon exposure to the very common palladium catalyst, the conceptually designed N-alkenyl iodobiaryls undergo a sequential carbopalladation/C-H activation to build polycyclic frameworks. These novel unique frameworks may provide structure sources in fragment-based drug discovery.