26525-40-6Relevant academic research and scientific papers
Iterative Assembly of Macrocyclic Lactones using Successive Ring Expansion Reactions
Stephens, Thomas C.,Lawer, Aggie,French, Thomas,Unsworth, William P.
supporting information, p. 13947 - 13953 (2018/09/14)
Macrocyclic lactones can be prepared from lactams and hydroxyacid derivatives via an efficient 3- or 4-atom iterative ring expansion protocol. The products can also be expanded using amino acid-based linear fragments, meaning that macrocycles with precise
