265322-97-2Relevant academic research and scientific papers
Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase
Esteban-Gamboa, Antonio,Balzarini, Jan,Esnouf, Robert,De Clercq, Erik,Camarasa, María-José,Pérez-Pérez, María-Jesús
, p. 971 - 983 (2007/10/03)
A series of acyclic phosphonate derivatives of thymine has been synthesized and tested as multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase. The compounds synthesized include 1- (phosphonoalkyl)thymines with six to nine methyl
