265324-40-1

Basic information

• Product Name: 2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2,6-dimethyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester
• Synonyms: 2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2,6-dimethyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 265324-40-1
• Molecular Weight: 660.213
• Mol File: 265324-40-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2,6-dimethyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2,6-dimethyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester(265324-40-1)
• EPA Substance Registry System: 2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-6-(2,6-dimethyl-pyrimidin-4-ylcarbamoyl)-2-oxo-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester(265324-40-1)

Safety Data

• Hazardous Substances Data: 265324-40-1(Hazardous Substances Data)

Upstream product

• 461-98-3 4-amino-2,6-dimethylpyrimidine 
• 201230-82-2 carbon monoxide 
• 199861-90-0 2-{2-[7-chloro-3-(3.5-dimethylphenyl)-6-iodo-2-oxo-1,2-dihydroquinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester 
• 199861-89-7 7-chloro-3-(3,5-dimethylphenyl)-4-hydroxy-6-iodo-1H-quinolin-2-one 
• 199861-83-1 4-chloro-2-[2-(3,5-dimethylphenyl)-acetylamino]-5-iodo-benzoic acid methyl ester 
• 199850-56-1 methyl 2-amino-4-chloro-5-iodobenzoate 
• 5900-58-3 2-amino-4-chloro-benzoic acid methyl ester 

Relevant articles and documents

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides

SAR studies which focused upon the C-6 position of a recently described series of quinolone gonadotropin releasing hormone antagonists are reported. Synthetic access to diverse quinolone-6-carboxamides was achieved via the palladium-catalyzed amino-carbonylation reactions of iodide 4 with various amines. Amides related to 9y were especially potent, functional antagonists of rat and human GnRH receptors. (C) 2000 Elsevier Science Ltd. All rights reserved.