26537-53-1Relevant academic research and scientific papers
Sydnone-coumarins as clickable turn-on fluorescent sensors for molecular imaging
Audisio, Davide,Bregant, Sarah,Clavier, Gilles,Decuypère, Elodie,Pieters, Grégory,Riomet, Margaux,Sallustrau, Antoine,Taran, Frédéric,Thai, Robert
, p. 10758 - 10761 (2018)
Copper-catalyzed and copper-free sydnone-alkyne cycloaddition reactions have emerged as complementary click tools for chemical biology but their use in bioorthogonal labeling is still in its infancy. Herein, combinations of alkynes and coumarin-sydnones were screened for their ability to generate pyrazole products displaying strong fluoroscence enhancement compared to reactants. One sydnone was identified as a particularly suitable new turn-on probe for protein labeling.
Visible-light induced photo-click and release strategy between monoarylsydnone and phenoxylfumarate
Li, Baolin,Liu, Hui,Shen, Xin,Xie, Xinyu,Yu, Zhipeng,Zhao, Xiaohu,Zheng, Tingting,Zheng, Yuanqin
supporting information, p. 8135 - 8138 (2021/08/23)
We report a visible-light induced photo-click and release platform between monoarylsydnone (MASyd) and phenoxylfumarates. The pyrazoline produced by the cycloaddition undergoes a photo-aromatization to form a fluorescent pyrazole. Meanwhile, the photo-aro
4-Halogeno-sydnones for fast strain promoted cycloaddition with bicyclo-[6.1.0]-nonyne
Plougastel, Lucie,Koniev, Oleksandr,Specklin, Simon,Decuypere, Elodie,Créminon, Christophe,Buisson, David-Alexandre,Wagner, Alain,Kolodych, Sergii,Taran, Frédéric
supporting information, p. 9376 - 9378 (2014/08/05)
New sydnone derivatives have been synthesized and screened for their capacity to undergo fast copper-free cycloaddition reaction with bicyclo-[6.1.0]-nonyne. The influences of substitution in positions N-3 and C-4 of sydnones have been particularly studied leading to the identification of highly reactive partners for bio-orthogonal ligation reactions.
