265648-71-3

Upstream product

• 193143-30-5 di-tert-butyl 2,2'-((2-(benzyl(2-(tert-butoxy)-2-oxoethyl)amino)ethyl)azanediyl)diacetate 
• 1201814-00-7 (S)-di-tert-butyl 2,2'-(1-hydroxy-3-phenylpropan-2-ylazanediyl)diacetate 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 186349-54-2 di-tert-butyl 2,2'-((2-((2-(tert-butoxy)-2-oxoethyl)amino)ethyl)azanediyl)diacetate 
• 112670-62-9 (2S)-2-amino-N-(2-aminoethyl)-3-phenylpropanamide 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 63-91-2 L-phenylalanine 

Downstream Products

• 748781-94-4 (S)-4-benzyl-3,6,9-tirs(carboxymethyl)-1,11-bis(methylamino)-3,6,9-triazaundeca-1,11-dione 

Relevant academic research and scientific papers

Application of aziridinium ring opening for preparation of optically active diamine and triamine analogues: highly efficient synthesis and evaluation of DTPA-based MRI contrast enhancement agents

Ring opening of aziridinium ions with nitrogen nucleophiles was applied to the highly efficient synthesis of optically active vicinal diamines and diethylene triamine pentaacetic acid (DTPA) analogues as potential magnetic resonance imaging (MRI) contrast enhancement agents. The synthetic method features a column-free isolation of the regiospecific and stereospecific nucleophilic substitution products of enantiomerically enriched aziridinium ions in excellent yield.

Synthesis and characterization of various benzyl diethylenetriaminepentaacetic acids (dtpa) and their paramagnetic complexes, potential contrast agents for magnetic resonance imaging

Four derivatives of diethylenetriaminepentaacetic acid (=3,6,9- tris(carboxymethyl)-3,6,9-triazaundecanedioic acid (H5dtpa)), potential contrast agents for magnetic resonance imaging (MRI), carrying benzyl groups at various positions of the par