265657-41-8

Usage

Structure

1H-1,2,3-Triazole-4-carboxylic acid, 5-methyl-1-(4-methylphenyl)-, hydrazide is a heterocyclic organic compound containing a triazole and carboxylic acid moiety.

Functional groups

Triazole, carboxylic acid, methyl, and phenyl groups.

Appearance

Unknown, but likely a solid or crystalline substance.

Solubility

Unknown, but may be soluble in organic solvents such as ethanol or methanol.

Stability

Stable under normal conditions, but sensitive to heat, light, or moisture.

Reactivity

Reacts with various reagents to form complex organic molecules.

Applications

Used in pharmaceuticals and material sciences as a building block for synthesizing complex organic molecules.

Biological activity

Studied for its potential as an antifungal agent.

Medicinal chemistry

Under investigation for its potential application in the field of medicinal chemistry.

Upstream product

• 210159-05-0 5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid 
• 2101-86-2 p-methylazidobenzene 
• 265657-43-0 5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-carboxylic acid ethyl ester 
• 106-49-0 p-toluidine 

Downstream Products

• 1333229-34-7 C₂₁H₁₉N₅O 
• 1015868-11-7 C₁₆H₁₇N₅O 

Relevant academic research and scientific papers

Synthesis of 5-(1,2,3-Triazol-4-yl)-1,3,4-Oxa(thia) diazol-2-Amines as Antimicrobial Agents

AN EFFICIENT method for the synthesis of new 1,2,3-triazol-4-yl-1,3,4-oxadiazol-2-amines (4a-c) from phenyliso-thiocyanate and 1,2,3-triazolyl-4-hydrazides (3a-c) through cyclo-desulfurization in the presence of sodium acetate is reported. Also, cyclization of 3a-c with concentrated H2SO4 afforded the corresponding triazol-4-ylthiadiazoles)6a-c(. The new products were screened for their antimicrobial activities, and compounds; 4a-c showed excellent antimicrobial activities compared with the reference drugs. Also, the minimum inhibitory concentration (MIC) against the tested organisms was determined in which, compounds 2c and 4a showed the lowest MIC.

Synthesis and characterization of some new 1,2,4-triazines containing 1,2,3-triazole

A series of 3-(1 -aryl-1 H-1,2,3-triazol-4-yl)-6-phenyl-1,2,4-triazines were synthesized by the reaction of 1-aryl-1tf-1,2,3-triazole-4-carbohydrazide with 2-bromo-1- phenylethanone and sodium acetate in refluxed EtOH and AcOH. Their structures were chara

Synthesis of 3-[5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-yl]-6- substituted-s-triazolo[3,4-b]-1,3,4-thiadiazoles

Several 3-[5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-yl]-6-substituted-1,3, 4-triazolo[3,4-b]-1,3,4-thiadiazoles have been synthesized and their structures established by elemental analysis and spectral data.

Synthesis of 3-[5-methyl-1-(4 -methylphenyl)-1,2,3-triazol-4 -yl]-6-aryl/heteroaryl-substituted-s-triazolo-[3,4-b] -1,3,4-thiadiazoles

Several 3-[5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-yl]-6 -substituted-1,3,4-triazolo[3,4-b]-1,3,4-thiadiazoles have been synthesized and the structures of these compounds were established by elemental analysis. MS, IR, and 1H NMR spectral data.

Synthesis of some 7H-s-triazolo[3,4-b]-1,3,4-thiadiazine derivatives

The cyclization of 1-amino-2-mercapto-5-[5-methyl-1-(4-methylphenyl)-1,2,3-triazol-4-yl]-l,3,4- triazole with various α-haloketone in absolute ethanol yields 7H-3-[5-methyl-1-(4-methylphenyl)-l,2,3-triazol-4-yl]-6-substituted-s- triazolo[3,4-b]-1,3,4-thiadiazines and their structures are established by elemental analysis, MS, IR and 1H NMR spectral data.