265975-30-2Relevant academic research and scientific papers
Highly efficient synthesis of flavonol 5-O-glycosides with glycosyl ortho-alkynylbenzoates as donors
Liao, Jin-Xi,Fan, Nai-Li,Liu, Hui,Tu, Yuan-Hong,Sun, Jian-Song
, p. 1221 - 1225 (2016)
With glycosyl ortho-alkynylbenzoates as donors, the highly efficient glycosylation of flavonoid 5-OH which are notorious for their low reactivity due to their involvement in the formation of strong intramolecular H-bonds was achieved under the catalysis of a Au(i) complex. Thus, a series of flavonoid 5-O-glycosides, including a kaempferol 5-O-disaccharide, were synthesized with good to excellent yields.
Selective cleavage of tert-butyldimethylsilylethers ortho to a carbonyl group by ultrasound
De Groot, Alex H.,Dommisse, Roger A.,Lemière, Guy L.
, p. 1541 - 1549 (2007/10/03)
A general method for the selective cleavage of tert- butyldimethylsilylethers ortho to a carbonyl group is established by sonication of a 0.1 M solution of the substrate in 1/1 (v/v) CH3OH/CCl4. Other phenolic tert-butyldimethylsilylethers are unaffected. This reaction performed on flavanoids is completed within 3 h and no special workup is required. Other substrates are also investigated and a mechanism is proposed. (C) 2000 Elsevier Science Ltd.
