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2-Imidazolidinethione, 4,5-dihydroxy-1-methyl-, commonly known as methimazole, is a chemical compound that plays a significant role in the medical field as an antithyroid agent. It is particularly effective in the treatment of hyperthyroidism, a condition characterized by the overproduction of thyroid hormones by the thyroid gland. Methimazole functions by inhibiting the enzyme thyroperoxidase, which in turn limits the synthesis of thyroid hormones. Despite its effectiveness, the use of methimazole must be closely monitored by healthcare professionals due to potential side effects.

265986-74-1

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265986-74-1 Usage

Uses

Used in Medical Applications:
2-Imidazolidinethione, 4,5-dihydroxy-1-methylis used as an antithyroid agent for the treatment of hyperthyroidism. It is effective in managing the overproduction of thyroid hormones by inhibiting the enzyme thyroperoxidase, thus helping to regulate the patient's thyroid hormone levels.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Imidazolidinethione, 4,5-dihydroxy-1-methylis used as a key ingredient in the formulation of drugs designed to treat hyperthyroidism. Its ability to inhibit thyroperoxidase makes it a valuable component in the development of medications that can help control the symptoms and complications associated with this condition.

Check Digit Verification of cas no

The CAS Registry Mumber 265986-74-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,5,9,8 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 265986-74:
(8*2)+(7*6)+(6*5)+(5*9)+(4*8)+(3*6)+(2*7)+(1*4)=201
201 % 10 = 1
So 265986-74-1 is a valid CAS Registry Number.

265986-74-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,5-dihydroxy-1-methylimidazolidine-2-thione

1.2 Other means of identification

Product number -
Other names 4,5-dihydroxy-1-methyltetrahydro-2H-imidazole-2-thione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:265986-74-1 SDS

265986-74-1Downstream Products

265986-74-1Relevant academic research and scientific papers

New access to thioglycolurils by condensation of 4,5-dihydroxyimidazolidin-2-ones(thiones) with HSCN

Baranov, Vladimir V.,Nelyubina, Yulia V.,Kravchenko, Angelina N.,Kolotyrkina, Natalya G.,Biriukova, Ksenia A.

, p. 6085 - 6088 (2015)

A general and highly effective protocol for the direct synthesis of mono- and dithioglycolurils containing various substituents at the 1,3-nitrogen atoms has been developed based on the condensation of easily accessible dihydroxyimidazolidin-2-ones with HSCN under mild reactions conditions.

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