265994-82-9Relevant academic research and scientific papers
Novel potassium channel openers. Part 4: Transformation of the 1,4- benzoxazine skeleton into 1,4-benzothiazine, 1,2,3,4-tetrahydroquinoline, 1,2,3,4-tetrahydroquinoxaline, indoline, and 1,5-benzoxazepine
Matsumoto, Yuzo,Tsuzuki, Ryuji,Matsuhisa, Akira,Yoden, Toru,Yamagiwa, Yoko,Yanagisawa, Isao,Shibanuma, Tadao,Nohira, Hiroyuki
, p. 393 - 404 (2007/10/03)
As part of a search for a new potassium channel opener, the 1,4- benzoxazine skeleton derived from the benzopyran skeleton of cromakalim, was transformed into other fused rings such as 1,4-benzothiazine, 1,2,3,4- tetrahydroquinoline, 1,2,3,4-tetrahydroqui
