26620-22-4

Basic information

• Product Name: (1R,2R)-cyclopentane-1,2-diyl diacetate
• CAS NO: 26620-22-4
• Molecular Formula: C₉H₁₄O₄
• Molecular Weight: 186.2051
• Mol File: 26620-22-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 228.5°C at 760 mmHg
• Flash Point: 105.1°C
• Density: 1.11g/cm³
• Vapor Pressure: 0.0734mmHg at 25°C
• Refractive Index: 1.455
• CAS DataBase Reference: (1R,2R)-cyclopentane-1,2-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-cyclopentane-1,2-diyl diacetate(26620-22-4)
• EPA Substance Registry System: (1R,2R)-cyclopentane-1,2-diyl diacetate(26620-22-4)

Safety Data

• Hazardous Substances Data: 26620-22-4(Hazardous Substances Data)

Usage

General Description

(1R,2R)-cyclopentane-1,2-diyl diacetate is a chemical compound with the molecular formula C9H14O4. It is a diester formed by the condensation of two molecules of acetic acid with a cyclopentane-1,2-diol. (1R,2R)-cyclopentane-1,2-diyl diacetate is commonly used as a reagent in organic synthesis to introduce the cyclopentane-1,2-diyl diacetate motif into various molecules. It has applications in the pharmaceutical and fragrance industries, as well as in the production of other organic compounds. (1R,2R)-cyclopentane-1,2-diyl diacetate is a colorless liquid with a fruity odor and is flammable. It should be handled with care using appropriate safety precautions.

Upstream product

• 5057-99-8 trans-cyclopentane-1,2-diol 
• 108-24-7 acetic anhydride 

Downstream Products

• 542-92-7 cyclopenta-1,3-diene 
• 99493-88-6 (R)-2-hydroxycyclopentanone 
• 147333-12-8 (2S)-2-hydroxycyclopentan-1-one 
• 1365970-45-1 (S)-2-(((((1R,2R)-2-(allyloxy)cyclopentyloxy)carbonyl)amino)-3,3-dimethylbutyric acid) 
• 930-46-1 (1R,2R)-cyclopentane-1,2-diol 
• 864658-69-5 (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol 
• 864658-68-4 (R)-2-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxymethyl]-oxirane 
• 864658-76-4 [(R)-1-((1S,2R)-2-Methoxymethoxy-cyclopentyloxymethyl)-undec-3-ynyloxymethyl]-benzene 
• 864658-67-3 (1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentanol 
• 864658-75-3 (1S,2R)-2-Methoxymethoxy-cyclopentanol 
• 241147-40-0 (1R,2R)-2-Methoxymethoxy-cyclopentanol 
• 20520-67-6 (1R,2R)-2-hydroxycyclopentyl acetate 
• 133442-59-8 (R,R)-1,2-diacetoxycyclopentane 
• 105663-23-8 (S,S)-1,2-diacetoxycyclopentane 

Relevant articles and documents

Synthesis of non-THF analogs of acetogenin toward simplified mimics

Acetogenin analogs in which the bis-adjacent THF ring was replaced with an enantioselectively synthesized 1,2-cyclopentanediol bis-ether skeleton were synthesized to obtain simplified mimics, and their inhibitory effect on mitochondrial NADH-ubiquinone oxidoreductase (complex I) was examined. The results clearly demonstrate that the 1,2-cyclopentanediol bis-ether motif can substitute for the bis-THF ring while maintaining very potent inhibitory activity at the nanomolar level.

Direct one step mono-functionalisation of symmetrical 1,2-diols

The mono-functionalisation of meso- and C2-symmetric diols has been achieved via the use of a new lanthanide(III) chloride catalysed acylation reaction. (C) 2000 Elsevier Science Ltd.