133442-59-8

Upstream product

• 108-05-4 vinyl acetate 
• 5057-99-8 trans-cyclopentane-1,2-diol 
• 26620-22-4 (+/-)-trans-1,2-diacetoxycyclopentane 
• 20520-67-6 trans-2-acetoxycyclopentanol 
• 108-24-7 acetic anhydride 

Downstream Products

• 542-92-7 cyclopenta-1,3-diene 
• 20520-67-6 (+/-)-cis-1-acetoxy-2-hydroxycyclopentane 
• 930-46-1 (1R,2R)-cyclopentane-1,2-diol 
• 20520-67-6 (1R,2R)-2-hydroxycyclopentyl acetate 
• 63261-45-0 (S,S)-cyclopentane-1,2-diol 
• 20520-67-6 (S,S)-2-acetoxycyclopentan-1-ol 
• 105663-23-8 (S,S)-1,2-diacetoxycyclopentane 
• 241147-40-0 (1R,2R)-2-Methoxymethoxy-cyclopentanol 
• 864658-75-3 (1S,2R)-2-Methoxymethoxy-cyclopentanol 
• 864658-67-3 (1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentanol 
• 864658-76-4 [(R)-1-((1S,2R)-2-Methoxymethoxy-cyclopentyloxymethyl)-undec-3-ynyloxymethyl]-benzene 
• 864658-68-4 (R)-2-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxymethyl]-oxirane 
• 864658-69-5 (R)-1-[(1R,2S)-2-((R)-2-Benzyloxy-dodec-4-ynyloxy)-cyclopentyloxy]-5-trimethylsilanyl-pent-4-yn-2-ol 
• 1365970-45-1 (S)-2-(((((1R,2R)-2-(allyloxy)cyclopentyloxy)carbonyl)amino)-3,3-dimethylbutyric acid) 

Relevant academic research and scientific papers

Synthesis of non-THF analogs of acetogenin toward simplified mimics

Acetogenin analogs in which the bis-adjacent THF ring was replaced with an enantioselectively synthesized 1,2-cyclopentanediol bis-ether skeleton were synthesized to obtain simplified mimics, and their inhibitory effect on mitochondrial NADH-ubiquinone oxidoreductase (complex I) was examined. The results clearly demonstrate that the 1,2-cyclopentanediol bis-ether motif can substitute for the bis-THF ring while maintaining very potent inhibitory activity at the nanomolar level.

Kinetic resolution of trans-2-acetoxycycloalkan-1-ols by lipase-catalysed enantiomerically selective acylation

Kinetic resolution of a series of racemic trans-cycloalkane-1,2-diol monoacetates rac-2a-d was performed by enantiomerically selective transesterification with vinyl acetate catalysed by commercial and our own-prepared fungal lipases to yield diacetates (

A one-step procedure for the monoacylation of symmetrical 1,2-diols

A series of lanthanide (III) salts have been shown to catalyze the monoacylation of symmetrical 1,2-diols by carboxylic acid anhydrides with surprisingly high selectivity.

Direct one step mono-functionalisation of symmetrical 1,2-diols

The mono-functionalisation of meso- and C2-symmetric diols has been achieved via the use of a new lanthanide(III) chloride catalysed acylation reaction. (C) 2000 Elsevier Science Ltd.

Enzymatic Preparation of Optically Pure trans-1,2-Cycloalkanediols

trans-1,2-Cycloalkanediols (R,R)-1,4 and (S,S)-1,3 of high optical purities are prepared by enzymatic hydrolysis and estrification catalyzed by a lipase from Pseudomonas sp. (SAM II).

Enantioselective Hydrolysis of Five-membered-ring Acetates catalysed by Pseudomonas fluorescens Lipase

The racemic acetates of five-membered-ring alcohols were successfully resolved into the optically active alcohols with high optical purities by Pseudomonas fluorescens lipase.