266312-20-3 Usage
General Description
2,3,5-Trifluoropyridine-4-carboxaldehyde is a chemical compound with the molecular formula C7H3F3NO. It is a highly fluorinated aromatic aldehyde with a pyridine core and a carboxyl group. 2,3,5-TRIFLUOROPYRIDINE-4-CARBOXALDEHYDE is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. It is also employed as a reagent in organic synthesis and chemical research. 2,3,5-Trifluoropyridine-4-carboxaldehyde is known for its strong odor and must be handled with care due to its potential health hazards and flammability.
Check Digit Verification of cas no
The CAS Registry Mumber 266312-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,6,3,1 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 266312-20:
(8*2)+(7*6)+(6*6)+(5*3)+(4*1)+(3*2)+(2*2)+(1*0)=123
123 % 10 = 3
So 266312-20-3 is a valid CAS Registry Number.
266312-20-3Relevant articles and documents
Synthesis of difluorinated pyridinecarboxaldehyde via electrophilic fluorination
Ko, Yoon-Joo,Park, Kyung-Bae,Shim, Seung-Bo,Shin, Jung-Hyu
, p. 755 - 759 (2008/03/28)
An efficient synthesis of novel 3,5-difluoropyridine-4-carboxaldehyde using N-fluoro-benzenesulfonimide (NSFi) is described. Difluorination was achieved through the reaction of 3,5-dihalo-1,3-dioxolane pyridine with n-butyllithium followed by N-fluorobenzenesulfonimide at -120 °C in good to high yields. Maintaining the low temperature during the transmetallation was found to be critical for the selective formation of the difluoro-susbstitution over the monofluoro one.