26644-92-8

Basic information

• Product Name: 1-Penten-4-yn-3-ol, 3-methyl-5-phenyl-
• CAS NO: 26644-92-8
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Mol File: 26644-92-8.mol

Chemical Properties

• CAS DataBase Reference: 1-Penten-4-yn-3-ol, 3-methyl-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Penten-4-yn-3-ol, 3-methyl-5-phenyl-(26644-92-8)
• EPA Substance Registry System: 1-Penten-4-yn-3-ol, 3-methyl-5-phenyl-(26644-92-8)

Safety Data

• Hazardous Substances Data: 26644-92-8(Hazardous Substances Data)

Upstream product

• 78-94-4 methyl vinyl ketone 
• 536-74-3 phenylacetylene 
• 4440-01-1 lithium phenylacetylide 

Downstream Products

• 955033-38-2 (5-bromo-3-methylpent-3-en-1-ynyl)benzene 
• 1133296-14-6 C₁₅H₂₀OSi 
• 62156-61-0 2-methyl-5-phenylcyclopent-2-en-1-one 
• 113386-22-4 3-Methyl-2-(phenylmethyl)thiophene 
• 148802-08-8 (Z)-3-methyl-5-phenyl-2-penten-4-yn-1-ol 
• 149929-75-9 trans-3-methyl-5-phenyl-2-penten-4-yn-1-ol 

Relevant articles and documents

Stereospecific Decarboxylative Nazarov Cyclization Mediated by Carbon Dioxide for the Preparation of Highly Substituted 2-Cyclopentenones

Highly substituted 2-cyclopentenones were stereospecifically and regioselectively constructed with high catalytic efficiency through Lewis-acid catalyzed decarboxylative Nazarov cyclization of the cyclic carbonate derivative, which is prepared by reacting the propargyl alcohol with carbon dioxide in the presence of a silver catalyst. The stereochemistry of the 2-cyclopentenone is strictly controlled by the geometry of the alkene in the starting material. This method is applicable for various substrates.

Reactivity of 3-silyloxy-1,4-enynes: Gold(III)-catalyzed regioselective nucleophilic substitution

Gold-catalyzed reactions of 3-silyloxy-1,4-enynes with alcohols afford primary, secondary, and tertiary pent-2-en-4-ynyl ethers in moderate to excellent yields. The substitution proceeds with high regioselectivity. An initial cyclization providing five-me

A general and facile synthesis of substituted furans by palladium- catalyzed cycloisomerization of (Z)-2-en-4-yn-1-ols

A general and facile synthesis of furans, based on Pd(II)-catalyzed cycloisomerization of (Z)-2-en-4-yn-1-ols, is described. Cycloisomerization reactions are carried out at 25-100 °C in the presence of a very simple catalytic system, consisting of K2PdI4, under essentially neutral conditions. This new methodology is very versatile and can be applied to the synthesis of a variety of substituted furans, including particularly fragile, naturally occurring furans such as rosefuran. Efficient synthetic approaches for the regioselective synthesis of suitably substituted (Z)-2-en-4-yn-1-ols have been developed.

Catalytic isomerization of 1-alkynyl-2,3-epoxy alcohols to substituted furans: Succinct routes to furanoid fatty acids and difurylmethanes

A versatile procedure for the preparation of synthetically valuable 2,5- disubstituted and 2,3,5-trisubstituted furans via mercury(II)-mediated isomerization of 1-alkynyl-2,3-epoxy alcohols is described. Mercury(II)- catalyzed isomerization of alkynyl epoxides 3a-k derived from cyclic α- alkynyl allylic alcohols furnishes 2,3,5-substituted furans bearing an aldehyde or keto group on the C-2 side chain. The reaction is used in a succinct and efficient synthesis of the furanoid fatty acid F5. In contrast, the mercury(II)-catalyzed reaction of a series of alkynyl epoxides 3m-p lacking ring fusion affords difurylmethanes 5, presumably by the dimerization of intermediate 2-(α hydroxyalkyl)furans 4.