2666-65-1

Upstream product

• 1985-12-2 4-Bromophenyl isothiocyanate 
• 2617-78-9 N-(4-bromophenyl)formamide 
• 345923-51-5 methyl N-4-bromophenyl-N-formyldithiocarbamate 
• 33554-73-3 1-bromo-4-isocyanobenzene 

Downstream Products

• 103-88-8 4-bromoacetanilide 
• 6341-55-5 N,N'-bis(p-bromophenyl)urea 
• 1160132-62-6 N,N',N-tris(4-bromophenyl)guanidine 
• 143932-79-0 3-<4-bromophenyl>-2-chloro-4-imino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine hydrochloride 
• 143932-81-4 3-<4-bromophenyl>-2-chloro-4-imino-5,6-dimethylthieno<2,3-d>pyrimidine hydrochloride 
• 33554-73-3 1-bromo-4-isocyanobenzene 
• 143770-37-0 2-amino-3-<4-bromophenyl>-4-imino-5,6,7,8-tetrahydro<1>benzothieno<2,3-d>pyrimidine 
• 143770-25-6 4-<4-bromophenyl>-5-imino-6,7-dimethyltetrazolo<1,5-a>thieno<3,2-e>pyrimidine 
• 143770-23-4 4-<4-bromophenyl>-5-imino-6,7,8,9-tetrahydro<1>benzothieno<3,2-e>tetrazolo<1,5-a>pyrimidine 
• 1147492-22-5 2-(4-bromophenylimino)-4,5-bis(5-methyl-2-furyl)-1,3-dioxole 
• 1227043-17-5 N,N-dibutyl-7-[(4-bromophenyl)imino]-7H-chromeno[2',3':4,5]pyrimido[1,6-a]benzimidazol-3-amine 
• 1227043-16-4 N,N-diethyl-7-[(4-bromophenyl)imino]-7H-chromeno[2',3':4,5]pyrimido[1,6-a]benzimidazol-3-amine 
• 1273585-27-5 (Z)-2-(4-bromophenylimino)-4,5-diphenyl-1,3-oxathiole 

Relevant academic research and scientific papers

Synthetic method of N-dichloromethylene aniline derivative

The invention discloses a synthetic method of an N-dichloromethylene aniline derivative represented by the formula II, wherein the synthesis method comprises the steps: with an isonitrile compound represented by the formula I as a raw material, in an organic solvent and under an action of iodobenzene dichloride represented by the formula III, carrying out a stirring reaction at the temperature of 0-50 DEG for 0.5-5 hours, and after the reaction is finished, separating and purifying the reaction liquid to obtain the N-dichloromethylene aniline derivative represented by the formula II. The synthetic method has the advantages of small toxicity of a chlorine source, environmental friendliness, mild reaction conditions, good universality of functional groups, convenience in operation and the like.

Method for preparing N-dichloro methylene aniline type compound

The invention discloses a method for preparing a N-dichloro methylene aniline type compound of a formula II as shown in the description. The method comprises the following steps: by taking an isonitrile type compound of the formula I as shown in the description as a raw material, in an organic solvent, under the action of N-cholosuccinimide of a formula III as shown in the description, stirring the raw material to react for 0.5-5 hours at 0-50 DEG C, after the reaction is completed, performing liquid separation and purification to obtain the N-dichloro methylene aniline type compound of formula II as shown in the description. The method disclosed by the invention has the advantages of being small in chlorine source toxicity, good in environmental friendliness, gentle in reaction condition, good in functional universality, simple and convenient to operate and the like.

Methyl n-aryl-n-formyldithiocarbamates and fluorination thereof

By reaction of unsubstituted and substituted in the benzene ring formanilides with carbon disulfide and potassium hydroxide in dimethylformamide followed by methylation with methyl iodide were prepared methyl N-aryl-N-formyldithiocarbamates. The reaction of methyl N-4-bromophenyl-N-formyldithiocarbamate with SF4 furnished 4-bromo-N-difluorornethyl-N-trifluoromethylaniline.