26668-70-2Relevant academic research and scientific papers
DIAZO COMPOUNDS IN THE 1,2,4-TRIAZOLE SERIES. II. STRUCTURE AND TRANSFORMATIONS OF THE PRODUCTS FROM DIAZOTIZATION OF 1-METHYL-3-AMINO-5-R-1,2,4-TRIAZOLES
Stepanov, S. D.,Pevzner, M. S.,Temchenko, T. P.
, p. 1935 - 1940 (2007/10/02)
Unstable solutions of diazonium salts are formed during the diazotization of 1-methyl-3-amino-5-R-1,2,4-triazoles.When treated with alkali, the diazonium salts change into the Z- and E-diazoates.The pKa values for the E-diazoate-E-diazohydroxide equilibrium were determined.Acidification of solutions of the E-diazohydroxides leads the diazonium salts.In the pH region where the joint presence of the diazohydroxide and diazonium forms is possible the solutions of the diazo compounds exhibited enhanced instability.
113. Notiz ueber die Reaktion von Methylhydrazin mit N-Cyano-azomethinen. Abhaengigkeit des Reaktionsverlaufs von der Natur der Abgangsgruppe
Kristinsson, Haukur,Winkler, Tammo
, p. 1129 - 1133 (2007/10/02)
The reaction of methylhydrazine with N-cyanoazomethines 1 containing a thioalkyl leaving group yields the 3-amino-1,2,4-triazole derivatives 2, whereas the N-cyanoazomethines 1 containing an alkoxy leaving group give the isomeric 5-amino-1,2,4-triazoles 3.The yields are excellent and the position selectivity is high.The structures of the 1,2,4-triazole derivatives were determined with the aid of proton-coupled 13C-NMR. spectra.
