266682-90-0

Basic information

• Product Name: C₁₃H₁₉ClNO₆P
• CAS NO: 266682-90-0
• Molecular Weight: 351.724
• Mol File: 266682-90-0.mol

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₉ClNO₆P(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₉ClNO₆P(266682-90-0)
• EPA Substance Registry System: C₁₃H₁₉ClNO₆P(266682-90-0)

Safety Data

• Hazardous Substances Data: 266682-90-0(Hazardous Substances Data)

Upstream product

• 123-31-9 hydroquinone 
• 51980-60-0 (4-(2-methoxyethoxy)phenol) 
• 2491-20-5 L-alanine methyl ester hydrochloride 
• 266682-86-4 C₉H₁₁Cl₂O₄P 

Relevant articles and documents

Enhancing the aqueous solubility of d4T-based phosphoramidate prodrugs

A range of polyether para-substituted phosphoramidates were synthesised and found to have substantially elevated aqueous solubilities compared to the underivatised parent prodrug. A 30-fold increase in aqueous solubility could be achieved without a substantial decrease of in vitro activity against HIV-1. Replacement of the aryl (i.e. phenolic) moiety by tyrosine led to a substantial enhancement in aqueous solubility but also to a decrease in antiviral potency. A previously unobserved trend was identified, relating increased aryl substituent steric bulk to decreased antiviral activity. (C) 2000 Elsevier Science Ltd. All rights reserved.