26685-47-2Relevant academic research and scientific papers
Soft cannabinoid analogues as potential anti-glaucoma agents
Buchwald,Browne,Wu,Ji,Bodor
, p. 196 - 201 (2007/10/03)
Cannabinoids have intraocular pressure (IOP) lowering effects, thus, they have a therapeutic potential in the treatment of glaucoma. Unfortunately, in the same time, they show CNS and cardiovascular effects as well. Our aim was to develop a safer, cannabi
Drugs derived from cannabinoids. 1. Nitrogen analogs, benzopyranopyridines and benzopyranopyrroles
Pars,Granchelli,Razdan,Keller,Teiger,Rosenberg,Harris
, p. 445 - 454 (2007/10/05)
Various nitrogen analogs of Δ(6a,10a) tetrahydrocannabinol were synthesized by a general procedure described in an earlier communication. Minimum effective doses (MED(50's)) and lethal doses (LD(50's)) were determined by a modified Irwin mouse screen afte
