26686-38-4Relevant academic research and scientific papers
Amino acid-based H2S donors:N-thiocarboxyanhydrides that release H2S with innocuous byproducts
Kaur, Kuljeet,Enders, Patrick,Zhu, Yumeng,Bratton, Abigail F.,Powell, Chadwick R.,Kashfi, Khosrow,Matson, John B.
supporting information, p. 5522 - 5525 (2021/06/12)
A library ofN-thiocarboxyanhydrides (NTAs) derived from natural amino acids with benign byproducts and controlled H2S-release kinetics is reported. Minimal acutein vitrotoxicity was observed in multiple cell lines, while longer-term toxicity in cancer cells was observed, with slow-releasing donors exhibiting the greatest cytotoxic effects.
