267007-97-6Relevant articles and documents
An efficient method for the synthesis of 4,5-disubstituted catechols
Ma, Tingli,Kojima, Takahiko,Matsuda, Yoshihisa
, p. 747 - 748 (2007/10/03)
4,5-Disubstituted catechols were prepared in high yields via successive Friedel-Crafts acylation in the presence of a Ti(IV) catalyst or I2 and reduction with triethylsilane of veratroles. This method provides an effective and well-regulated synthetic strategy toward catechol derivatives having a variety of substituents at the 4- and 5- positions.