26706-86-5

Upstream product

• 110-45-2 isopentyl formate 
• 589-92-4 1-methylcyclohexan-4-one 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 104174-44-9 1-allyl-5-methyl-2-oxo-cyclohexanecarbaldehyde 
• 823-55-2 2,4-dimethylcyclohexanone 
• 90607-98-0 4-Methyl-2-methylaminomethylen-cyclohexanon 
• 32286-86-5 5-methyl-1-phenyl-4,5,6,7-tetrahydro-1H-indazole 
• 910640-91-4 3-[4-((S)-2,3-dihydroxypropoxy)-3,5-dimethylphenyl]-1-(3-ethyl-5-methyl-4,5,6,7-tetrahydro-benzo[c]thiophen-1-yl)propan-1-one 
• 910640-87-8 C₂₂H₂₈O₂S 
• 910640-84-5 C₂₂H₂₆O₂S 
• 97212-79-8 5-Methyl-2-oxo-cyclohexan-carbonsaeure-cyclohexylamid 
• 90942-71-5 5-Methyl-2-oxo-cyclohexan-carbonsaeure-methylamid 
• 85808-21-5 4-methyl-2-(phenylsulfanyl)cyclohex-2-enone 
• 85808-19-1 2-Diazo-4-methyl-cyclohexanone 
• 92330-78-4 4-Methyl-2-cyclohexylaminomethylen-cyclohexanon 

Relevant academic research and scientific papers

Novel S1P1 receptor agonists - Part 2: From bicyclo[3.1.0] hexane-fused thiophenes to isobutyl substituted thiophenes

Previously, we reported on the discovery of a novel series of bicyclo[3.1.0]hexane fused thiophene derivatives that serve as potent and selective S1P1 receptor agonists. Here, we discuss our efforts to simplify the bicyclohexane fused thiophene

REGIOSPECIFIC SYNTHESIS OF α-(PHENYLTHIO)CYCLOALKENONES AND OF α-PHENYL-α-(PHENYLTHIO)KETONES VIA αα-ADDITION OF PHENYLSULPHENYL CHLORIDE TO α-DIAZOKETONES

Cyclic α-diazoketones react with phenylsulphenyl chloride at room temperature to furnish α-chloro-α-(phenylthio)cycloalkanones which undergo ready dehydrochlorination to α-(phenylthio)cycloalkenones when treated with triethylamine; acyclic, terminal α-diazoketones also furnish α-chloro-α-(phenylthio)adducts which are useful electrophiles in the synthesis of α-phenyl-α-(phenylthio)ketones.