26717-84-0

Usage

Uses

Used in Food and Beverage Industry:
Ethyl 3-methoxy-4,4,4-trifluoro-2-butenoate is used as a flavoring agent for its fruity scent, enhancing the taste and aroma of various food products such as candies, baked goods, and soft drinks.
Used in Perfumery and Personal Care Industry:
Ethyl 3-methoxy-4,4,4-trifluoro-2-butenoate is utilized as a fragrance ingredient in the production of perfumes and other personal care products, contributing to their pleasant and appealing scents.
Used in Pharmaceutical Research:
Ethyl 3-methoxy-4,4,4-trifluoro-2-butenoate is studied for its potential pharmaceutical applications, including its use as an anti-inflammatory and anti-cancer agent, indicating its possible role in the development of new therapeutic agents.
While Ethyl 3-methoxy-4,4,4-trifluoro-2-butenoate is considered relatively stable and non-reactive under normal conditions, it is important to handle and store it with care due to its potential health and environmental hazards.

InChI:InChI=1/C7H9F3O3/c1-3-13-6(11)4-5(12-2)7(8,9)10/h4H,3H2,1-2H3/b5-4-

Upstream product

• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 
• 77-78-1 dimethyl sulfate 
• 80-48-8 methyl p-toluene sulfonate 
• 116046-53-8 2-trifluoromethyl-3-oxobutanoic acid ethyl ester 

Downstream Products

• 119022-51-4 5-trifluoromethyl-3-hydroxy-1-methylpyrazole 
• 157162-16-8 methyl 3-hydroxy-5-(trifluoromethyl)thiophene-2-carboxylate 

Relevant academic research and scientific papers

Thienyloxypyridines and-pyrimidines useful as herbicidal agents

The present invention provides a herbicidal compound of formula I, methods for the preparation thereof and intermediates useful therefor. wherein X and Y are each independently O or S; Z is N or CR4.

Preparation of 4-hydroxy-2-trifluoromethylthiophene: A novel bioisostere of α,α,α-trifluoro-m-cresol

A simple and convenient four-step synthesis of 4-hydroxy-2- trifluoromethylthiophene (1) a novel bioisostere of α,α,α- trifluoro-m-cresol is reported. The key step is the condensation between ethyl 3-methoxy-4,4,4-trifluorocrotonate and methyl thioglycolate to form methyl 3-hydroxy-5- trifluoromethylthiophene-2-carboxylate (6). Hydrolysis of the ester followed by decarboxylation furnishes 1. Multi-hundred gram quantities of 1 have been obtained utilizing the present procedure.

Novel Perfluoroalkyl-Substituted Pyrazoles. 1. Hydroxypyrazoles

Addition of methylhydrazine to a variety of haloalkyl-substituted α,β-unsaturated esters gives 1,5-disubstituted 3-hydroxypyrazoles, in contrast to the more common synthesis from β-ketoesters, which gives 1,3-disubstituted 5-hydroxypyrazoles.This reaction is used to prepare several novel pyrazoles bearing haloalkyl substituents.Criteria for assignment of structures have been developed based on physical and spectroscopic properties of the isomers.The regiochemical preference in this addition is considered on the basis of steric, electronic, and mechanistic factors.