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CAS

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267226-07-3

3-(4-benzyloxy-phenyl)-4-ethyl-pyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 267226-07-3 Structure

  • Basic information

    1. Product Name: 3-(4-benzyloxy-phenyl)-4-ethyl-pyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid
    2. Synonyms:
    3. CAS NO:267226-07-3
    4. Molecular Formula:
    5. Molecular Weight: 439.467
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 267226-07-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(4-benzyloxy-phenyl)-4-ethyl-pyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(4-benzyloxy-phenyl)-4-ethyl-pyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid(267226-07-3)
    11. EPA Substance Registry System: 3-(4-benzyloxy-phenyl)-4-ethyl-pyrrolo[2,1,5-cd]indolizine-1,2-dicarboxylic acid(267226-07-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 267226-07-3(Hazardous Substances Data)

267226-07-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 267226-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,7,2,2 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 267226-07:
(8*2)+(7*6)+(6*7)+(5*2)+(4*2)+(3*6)+(2*0)+(1*7)=143
143 % 10 = 3
So 267226-07-3 is a valid CAS Registry Number.

267226-07-3Relevant articles and documents

Synthesis and pharmacology of a novel pyrrolo[2,1,5-cd] indolizine (NNC 45-0095), a high affinity non-steroidal agonist for the estrogen receptor

Jorgensen,Jacobsen,Christiansen,Bury,Kanstrup,Thorpe,Bain,Naerum,Wassermann

, p. 399 - 402 (2007/10/03)

1-Ethyl-2-(4-hydroxyphenyl)pyrrolo[2,1,5-cd]indolizine (NNC 45-0095) is a novel compound which represents the parent pharmacophore structure of a series of pyrrolo[2,1,5-cd]indolizine derivatives with mixed estrogen agonist/antagonist properties. NNC 45-0095 binds with high affinity to the estrogen receptor (IC50 = 9.5 nM) and exhibits full protection of bone loss in the ovariectomized mouse model for post-menopausal osteoporosis. (C) 2000 Elsevier Science Ltd. All rights reserved.

Synthesis and estrogen receptor binding affinities of novel pyrrolo[2,1,5-cd]indolizine derivatives

Jorgensen, Anker Steen,Jacobsen, Poul,Christiansen, Lise Brown,Bury, Paul S.,Kanstrup, Anders,Thorpe, Susan M.,Narum, Lars,Wassermann, Karsten

, p. 2383 - 2386 (2007/10/03)

A series of pyrrolo[2,1,5-cd]indolizine derivatives has been synthesized and evaluated as ligands for the estrogen receptor. Properly substituted mono- and di-hydroxy derivatives showed binding in the low nanomolar range in accordance with their structural resemblance to estrogen. (C) 2000 Elsevier Science Ltd.

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