26723-10-4

Basic information

• Product Name: L-Cysteine, N-acetyl-S-(phenylmethyl)-, ethyl ester
• CAS NO: 26723-10-4
• Molecular Formula: C14H19NO3S
• Molecular Weight: 281.376
• Mol File: 26723-10-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Cysteine, N-acetyl-S-(phenylmethyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Cysteine, N-acetyl-S-(phenylmethyl)-, ethyl ester(26723-10-4)
• EPA Substance Registry System: L-Cysteine, N-acetyl-S-(phenylmethyl)-, ethyl ester(26723-10-4)

Safety Data

• Hazardous Substances Data: 26723-10-4(Hazardous Substances Data)

Upstream product

• 953-18-4 S-benzyl-L-cysteine ethyl ester 
• 101762-41-8 4-acetoxyphenoxathiin 
• 101762-28-1 1-chloro-4-acetoxydibenzofuran 
• 101762-27-0 4-acetoxydibenzofuran 

Relevant articles and documents

Peptide Synthesis by Prior Thiol Capture. 2. Design of Templates for Intramolecular O,N-Acyl Transfer. 4,6-Disubstituted Dibenzofurans as Optimal Spacing Elements

A central feature of the strategy for amide bond formation by prior thiol capture is an intramolecular acyl transfer across a template that links the phenolic ester function of one peptide with an unsymmetrical disulfide involving the side chain of the N-terminal cysteine residue of a second peptide.The structures of the 4-hydroxy-6-mercaptodibenzofuran (3) and 4-hydroxy-6-mercaptophenoxythiin (4) are established by 1H NMR spectra of deuterated dibenzofuran and phenoxythiin derivatives.On the basis of the criterion of effective molarity, a dibenzofuran template for intramolecular acyl transfer is shown to be approximately 2 orders of magnitude more efficient than a phenoxythiin.An effective local concentration of ca. 5 M and a Hammett ρ value of 2.6 are observed for the intramolecular acyl-transfer reaction 1 -> 2.