267230-40-0

Basic information

• Product Name: 1,3-Pyrrolidinedicarboxylic acid, 4-[[(1R)-1-phenylethyl]amino]-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-
• CAS NO: 267230-40-0
• Molecular Formula: C20H30N2O4
• Molecular Weight: 362.469
• Mol File: 267230-40-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Pyrrolidinedicarboxylic acid, 4-[[(1R)-1-phenylethyl]amino]-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Pyrrolidinedicarboxylic acid, 4-[[(1R)-1-phenylethyl]amino]-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-(267230-40-0)
• EPA Substance Registry System: 1,3-Pyrrolidinedicarboxylic acid, 4-[[(1R)-1-phenylethyl]amino]-, 1-(1,1-dimethylethyl) 3-ethyl ester, (3R,4S)-(267230-40-0)

Safety Data

• Hazardous Substances Data: 267230-40-0(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 146256-98-6 4-oxo-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 
• 146256-99-7 tert-butyl 3-ethyl 4-hydroxypyrrolidine-1,3-dicarboxylate 
• 146257-00-3 2,5-Dihydro-pyrrole-1,3-dicarboxylic acid 1-tert-butylester 3-ethyl ester 

Downstream Products

• 388105-01-9 C₂₉H₄₀FN₅O₄S 
• 388109-47-5 (3S,4R)-3-Amino-4-[(S)-3-(4-fluorobenzyl)-piperidine-1-carbonyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 388109-46-4 (3R,4S)-3-[(S)-3-(4-fluorobenzyl)-piperidine-1-carbonyl]-4-[(R)-1-phenyl-ethylamino]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 895243-98-8 (3R,4S)-4-Amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester 

Relevant articles and documents

TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.

12-Helix formation in aqueous solution with short β-peptides containing pyrrolidine-based residues

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