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CAS

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146256-99-7

4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester, also known as (R, S)-Homoprotocatechuic acid 1,4-lactone, is a chemical compound derived from the natural product homoprotocatechuic acid, which is found in a variety of plants. 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester has been studied for its potential antioxidant, anti-inflammatory, and neuroprotective properties, and it has also been investigated as a potential treatment for neurological disorders. Additionally, it has been used as a precursor for the synthesis of other biologically active compounds. Overall, 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester has shown promise in various research areas and could have potential applications in pharmaceutical development and medical research.

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  • 146256-99-7 Structure

  • Basic information

    1. Product Name: 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester
    2. Synonyms: 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester;Ethyl 1-tert-butoxycarbonyl-4-hydroxypyrrolidine-3-carboxylate;4-hydroxy-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester;Ethyl 1-Boc-4-hydroxypyrrolidine-3-carboxylate;JHBUFXKTKCCCKA-UHFFFAOYSA-N
    3. CAS NO:146256-99-7
    4. Molecular Formula: C12H21NO5
    5. Molecular Weight: 259.29884
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 146256-99-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester(146256-99-7)
    11. EPA Substance Registry System: 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester(146256-99-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 146256-99-7(Hazardous Substances Data)

146256-99-7 Usage

Uses

Used in Pharmaceutical Development:
4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester is used as a precursor for the synthesis of other biologically active compounds, contributing to the development of new pharmaceuticals with potential therapeutic benefits.
Used in Antioxidant Applications:
In the field of health and nutrition, 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester is used as an antioxidant, helping to protect cells from oxidative damage and potentially reducing the risk of various diseases associated with oxidative stress.
Used in Anti-Inflammatory Applications:
4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester is used as an anti-inflammatory agent, potentially reducing inflammation and alleviating symptoms in various inflammatory conditions.
Used in Neuroprotective Applications:
In the field of neuroscience, 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester is used for its neuroprotective properties, potentially offering protection to neurons and reducing the risk of neurodegenerative diseases.
Used in Neurological Disorder Treatment:
4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester is being investigated as a potential treatment for neurological disorders, due to its potential to protect and support the health of the nervous system.
Used in Biochemical Research:
In the scientific community, 4-Hydroxy-1,3-pyrrolidinedicarboxylic acid 1-(1,1-dimethylethyl) 3-ethyl ester is used as a research tool in biochemical studies, aiding in the understanding of various biological processes and the development of new therapeutic strategies.

Check Digit Verification of cas no

The CAS Registry Mumber 146256-99-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,2,5 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 146256-99:
(8*1)+(7*4)+(6*6)+(5*2)+(4*5)+(3*6)+(2*9)+(1*9)=147
147 % 10 = 7
So 146256-99-7 is a valid CAS Registry Number.

146256-99-7Relevant articles and documents

Synthesis, antimycobacterial and antibacterial activity of fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety

Zhang, Tingting,Shen, Weiyi,Liu, Mingliang,Zhang, Rui,Wang, Minghua,Li, Linhu,Wang, Bin,Guo, Huiyuan,Lu, Yu

, p. 73 - 85 (2015)

A series of novel fluoroquinolone derivatives containing an 3-alkoxyimino-4-(cyclopropylanimo)methylpyrrolidine moiety were designed, synthesized and evaluated for their biological activity. Our results revealed that 19b2 shows good activity against MTB H

TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

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Paragraph 00487-00488, (2021/12/08)

The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.

Peptides containing an arginine mimetic for the treatment of bone metabolic disorders, their production, and drugs containing these compounds

-

, (2008/06/13)

Arginine mimetic peptides according to Formula I of this application have a stimulating effect on bone formation and are useful for the treatment of bone metabolic disorders.

Amidinopyrroline derivatives, processes for their production and pharmaceutical agents containing these compounds

-

, (2008/06/13)

Compound of formula (I) are disclosed STR1 as well as optically active isomers or pharmacologically acceptable salts thereof. The compounds are useful active ingredients in pharmaceutical compositions, and methods of treating osteoporosis, inflammation or

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