267235-95-0

Basic information

• Product Name: 3-BROMO-2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIDINE
• Synonyms: 3-BROMO-2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIDINE
• CAS NO: 267235-95-0
• Molecular Formula: C₁₄H₇BrF₄N₂
• Molecular Weight: 359.12
• Mol File: 267235-95-0.mol

Chemical Properties

• Appearance: /
• Density: 1.65±0.1 g/cm3(Predicted)
• PKA: -1.36±0.30(Predicted)
• CAS DataBase Reference: 3-BROMO-2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIDINE(267235-95-0)
• EPA Substance Registry System: 3-BROMO-2-(4-FLUOROPHENYL)-6-(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIDINE(267235-95-0)

Safety Data

• Hazardous Substances Data: 267235-95-0(Hazardous Substances Data)

Upstream product

• 372122-55-9 2-(4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine 

Downstream Products

• 401816-65-7 4-[2-(4-fluorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridin-3-yl]pyrimidin-2-yl methyl sulfide 

Relevant articles and documents

The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors

A series of pyrazolo[1,5-a]pyridine derivatives was designed and synthesized as novel potent p38 kinase inhibitors. Our approaches towards improving in vitro metabolism and in vivo pharmacokinetic properties of the series are described.

Fused pyrazole derivatives bieng protein kinase inhibitors

Compounds of Formula (I): salts or solvates or physiologically functional derivatives thereof, wherein Z is CH or N, and R1, (R2, and R4 are various substituent groups, are protein kinase inhibitors.