372122-55-9Relevant articles and documents
The identification of pyrazolo[1,5-a]pyridines as potent p38 kinase inhibitors
Cheung, Mui,Harris, Philip A.,Badiang, Jennifer G.,Peckham, Gregory E.,Chamberlain, Stanley D.,Alberti, Michael J.,Jung, David K.,Harris, Stephanie S.,Bramson, Neal H.,Epperly, Andrea H.,Stimpson, Stephen A.,Peel, Michael R.
scheme or table, p. 5428 - 5430 (2009/06/18)
A series of pyrazolo[1,5-a]pyridine derivatives was designed and synthesized as novel potent p38 kinase inhibitors. Our approaches towards improving in vitro metabolism and in vivo pharmacokinetic properties of the series are described.
Pyrazolo[1,5-a]pyridines as p38 kinase inhibitors
Stevens, Kirk L.,Jung, David K.,Alberti, Michael J.,Badiang, Jennifer G.,Peckham, Gregory E.,Veal, Jim M.,Cheung, Mui,Harris, Philip A.,Chamberlain, Stanley D.,Peel, Michael R.
, p. 4753 - 4756 (2007/10/03)
(Chemical Equation Presented) A convergent synthesis of substituted pyrazolo[1,5-a]pyridines has been achieved either via a regioselective [3 + 2] cycloaddition of N-aminopyridines with alkynes or by thermal cyclization of disubstituted azirines. Subseque
PROCESS FOR THE PREPARATION OF CHEMICAL COMPOUNDS
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Page/Page column 5-6, (2008/06/13)
The invention provides a process for preparing a compound of formula (I) and pharmaceutically acceptable derivatives thereof wherein: R0 and R1 are independently selected from H. halogen, C1-6alkyl, C1-6alkoxy.