267243-96-9

Upstream product

• 203200-31-1 1-[(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-5-phenylselanyl-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 203200-32-2 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-5-phenylselanyl-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 
• 267243-95-8 1-[3-O-(allyldimethylsilyl)-2-deoxy-5-O-(dimethoxytrityl)-4-C-(phenylseleno)-α-L-threo-pento-1,4-furanosyl]thymine 

Downstream Products

• 267244-05-3 5'-O-(dimethoxytrityl)-4'-C-[3-(N-trifluoroacetyl)aminopropyl]thymidine 
• 267243-99-2 4'-C-(3-azidopropyl)-3'-O-(tert-butyldimethylsilyl)-5'-O-(dimethoxytrityl)thymidine 
• 267243-97-0 3'-O-(tert-butyldimethylsilyl)-5'-O-(dimethoxytrityl)-4'-C-(3-hydroxypropyl)thymidine 
• 267244-01-9 4'-C-(3-azidopropyl)-5'-O-(dimethoxytrityl)thymidine 

Relevant academic research and scientific papers

Highly nuclease-resistant phosphodiester-type oligodeoxynucleotides containing 4′α-C-aminoalkylthymidines form thermally stable duplexes with DNA and RNA. A candidate for potent antisense molecules

The properties of phosphodiester oligodeoxynucleotides (ODNs) containing 4′α-C-aminomethyl, -ethyl, -propyl, and -N-(2-aminoethyl)carbamoylthymidines (1, 2, 4, and 5) as potential antisense molecules are investigated in detail. We developed new radical ch

Synthesis of oligodeoxynucleotides containing 4'-C-aminoalkylthymidines and their thermal stability and nuclease-resistance properties

To find the nuclease-resistant oligodeoxynucleotides (ODNs) with natural phosphodiester linkages, we designed and synthesized ODNs containing 4'-C- aminoalkylthymidines (1-4). We found that the ODNs containing 1, 2, 3 or 4 were more resistant to nucleolyt