26750-83-4

Basic information

• Product Name: 5-Allyl-2,3-dimethoxy-N-(2-hydroxyethyl)benzamide
• Synonyms: 5-Allyl-2,3-dimethoxy-N-(2-hydroxyethyl)benzamide;PC-56
• CAS NO: 26750-83-4
• Molecular Formula: C₁₄H₁₉NO₄
• Molecular Weight: 265.305
• Mol File: 26750-83-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 387.3°Cat760mmHg
• Flash Point: 188.1°C
• Appearance: /
• Density: 1.123g/cm³
• Vapor Pressure: 1.08E-06mmHg at 25°C
• Refractive Index: 1.532
• CAS DataBase Reference: 5-Allyl-2,3-dimethoxy-N-(2-hydroxyethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Allyl-2,3-dimethoxy-N-(2-hydroxyethyl)benzamide(26750-83-4)
• EPA Substance Registry System: 5-Allyl-2,3-dimethoxy-N-(2-hydroxyethyl)benzamide(26750-83-4)

Safety Data

• Hazardous Substances Data: 26750-83-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H19NO4/c1-4-5-10-8-11(14(17)15-6-7-16)13(19-3)12(9-10)18-2/h4,8-9,16H,1,5-7H2,2-3H3,(H,15,17)

Upstream product

• 22934-51-6 5-allyl-2-hydroxy-3-methoxybenzaldehyde 

Relevant articles and documents

Metal-Free Thermal Activation of Molecular Oxygen Enabled Direct α-CH2-Oxygenation of Free Amines

Direct oxidation of α-CH2 group of free amines is hard to achieve due to the higher reactivity of amine moiety. Therefore, oxidation of amines involves the use of sophisticated metallic reagents/catalyst in the presence or absence of hazardous oxidants under sensitive reaction conditions. A novel method for direct C-H oxygenation of aliphatic amines through a metal-free activation of molecular oxygen has been developed. Both activated and unactivated free amines were oxygenated efficiently to provide a wide variety of amides (primary, secondary) and lactams under operationally simple conditions without the aid of metallic reagents and toxic oxidants. The method has been applied to the synthesis of highly functionalized amide-containing medicinal drugs, such as O-Me-alibendol and -buclosamide.