267642-46-6Relevant articles and documents
FLUORESCENCE LABELING AGENT, PHOTODYNAMIC THERAPEUTIC AGENT AND PHTHALOCYANINE
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Paragraph 0068-0070, (2021/04/23)
PROBLEM TO BE SOLVED: To provide a phthalocyanine-based compound having excellent properties such as fluorescence intensity, light resistance and singlet oxygen generation ability suitable for a fluorescence labeling agent and a photodynamic therapeutic agent in a wavelength region of 800 nm or more. SOLUTION: This invention relates to salts of a phosphorus-containing phthalocyanine-based compound in which a phosphorus atom in a phosphorus compound expressed by formula: R5O-P-OR6 is coordinated with a phthalocyanine-based compound, and to a fluorescence labeling agent and a photodynamic therapeutic agent, which contain the salts of the phosphorus-containing phthalocyanine-based compound. In the formula, R5 and R6 are H, an aliphatic hydrocarbon group, -P(=O) R7R8, -C(=O) R9, -S(=O)2R10 or -SiR11R12R13; R7 and R8 are H, OH, an aliphatic hydrocarbon group, an aromatic hydrocarbon group, an alkoxyl group, or an aryloxy group; R9 is H, an aliphatic hydrocarbon group, or an aromatic hydrocarbon group; R10 is OH, an aliphatic hydrocarbon group, or an aromatic hydrocarbon group; and R11 to R13 are an aliphatic hydrocarbon group or an aromatic hydrocarbon group. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT