267644-49-5

Basic information

• Product Name: 2-Aminocarbonyl-5-nitrobenzofuran
• Synonyms: 2-Aminocarbonyl-5-nitrobenzofuran;2-BenzofurancarboxaMide, 5-nitro-;5-nitro-1-benzofuran-2-carboxamide
• CAS NO: 267644-49-5
• Molecular Formula: C9H6N2O4
• Molecular Weight: 206.15
• Product Categories: API intermediates
• Mol File: 267644-49-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 461.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.505±0.06 g/cm3(Predicted)
• PKA: 15.18±0.30(Predicted)
• CAS DataBase Reference: 2-Aminocarbonyl-5-nitrobenzofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Aminocarbonyl-5-nitrobenzofuran(267644-49-5)
• EPA Substance Registry System: 2-Aminocarbonyl-5-nitrobenzofuran(267644-49-5)

Safety Data

• Hazardous Substances Data: 267644-49-5(Hazardous Substances Data)

Usage

General Description

2-Aminocarbonyl-5-nitrobenzofuran, also known as ANBF, is a chemical compound that consists of a nitrobenzofuran core with an amino carbonyl group attached at the 2-position. It is an important building block in the synthesis of various organic compounds and has potential applications in pharmaceuticals and materials science. ANBF is known for its interesting electronic and photophysical properties, making it a valuable tool in the development of novel materials and compounds with unique optical and electronic characteristics. Its versatile reactivity and potential for further functionalization make it a promising candidate for use in a wide range of chemical and material applications.

Upstream product

• 125418-93-1 2-(2-formyl-4-nitrophenoxy)acetonitrile 
• 90036-16-1 5-nitrobenzofuran-2-carbonyl chloride 
• 10242-12-3 5-nitrobenzofuran-2-carboxylic acid 
• 6965-69-1 2-(2-formyl-4-nitrophenoxy)acetic acid 
• 90-02-8 salicylaldehyde 
• 6280-80-4 2-Formylphenoxyacetic acid 
• 97-51-8 5-Nitrosalicylaldehyde 
• 69604-00-8 ethyl 5-nitrobenzo[d]furan-2-carboxylate 

Downstream Products

• 183288-46-2 5-(1-piperazinyl)benzofuran-2-carboxamide 
• 163521-12-8 vilazodone 
• 53020-42-1 5-hydroxybenzofuran-2-carbonitrile 
• 916737-84-3 5-aminobenzofuran-2-carbonitrile 

Relevant articles and documents

Probes for imidazoline binding sites: Synthesis and evaluation of a selective, irreversible I2 ligand

An irreversible ligand (7) has been prepared based on the selective I2 ligand 2-BFI. Compound 7 displayed high affinity and selectivity for I2-sites and has been shown to irreversibly bind to these sites in rat brain. Compound 7 should, therefore, prove an invaluable tool for the further elucidation of I2-site function. (C) 2000 Elsevier Science Ltd. All rights reserved.

Pyrimidine heterocyclic compounds, pyrimidine heterocyclic compound salts, and preparation method and application thereof

The invention provides pyrimidine heterocyclic compounds, pyrimidine heterocyclic compound salts, and a preparation method and application thereof. According to the pyrimidine heterocyclic compounds provided by the invention, specific Rq is selected, so that the obtained compounds have favorable drug resistance and long half life when being used as the medicine for treating or preventing HIV. The compounds have the advantages of high activity, low toxicity and high stability.

PROCESS FOR THE PREPARATION OF VILAZODONE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF

The present invention provides a novel intermediate of vilazodone and its process of preparation. The present invention further provides a process for preparing vilazodone or a pharmaceutically acceptable salt thereof using said novel intermediate.