267659-63-2

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 4-[[2-bromo-5-[(methylsulfonyl)oxy]phenyl]methyl]-3-oxo-, 1,1-dimethylethyl ester
• CAS NO: 267659-63-2
• Molecular Formula: C17H23BrN2O6S
• Molecular Weight: 463.349
• Mol File: 267659-63-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-[[2-bromo-5-[(methylsulfonyl)oxy]phenyl]methyl]-3-oxo-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-[[2-bromo-5-[(methylsulfonyl)oxy]phenyl]methyl]-3-oxo-, 1,1-dimethylethyl ester(267659-63-2)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-[[2-bromo-5-[(methylsulfonyl)oxy]phenyl]methyl]-3-oxo-, 1,1-dimethylethyl ester(267659-63-2)

Safety Data

• Hazardous Substances Data: 267659-63-2(Hazardous Substances Data)

Upstream product

• 267659-62-1 methanesulfonic acid 4-bromo-3-methylphenyl ester 
• 14472-14-1 4-bromo-3-methylphenol 
• 76003-29-7 4-(t-butyloxycarbonyl)piperazin-2-one 
• 229640-29-3 methanesulfonic acid 4-bromo-3-bromomethylphenyl ester 

Downstream Products

• 267659-64-3 1-[2-Bromo-5-((methanesulfonyl)oxy)benzyl]-2-piperazinone hydrochloride 
• 254108-64-0 4-[1-(4-Cyano-3-fluorobenzyl)-5-imidazolylmethyl]-1-[2-bromo-5-((methanesulfonyl)-oxy)benzyl]-2-piperazinone 
• 676319-77-0 methanesulfonic acid 4-bromo-3-(2-oxo-piperazin-1-ylmethyl)-phenyl ester 

Relevant articles and documents

Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I

A series of macrocyclic piperazinone compounds with dual farnesyltransferase/geranylgeranyltransferase-I inhibitory activity was prepared. These compounds were found to be potent inhibitors of protein prenylation in cell culture. A hypothesis for the binding mode of compound 3o in FPTase is proposed.