267885-31-4Relevant articles and documents
Cyclin-dependent kinase inhibition by new C-2 alkynylated purine derivatives and molecular structure of a CDK2-inhibitor complex
Legraverend, Michel,Tunnah, Paul,Noble, Martin,Ducrot, Pierre,Ludwig, Odile,Grierson, David S.,Leost, Maryse,Meijer, Laurent,Endicott, Jane
, p. 1282 - 1292 (2007/10/03)
A new series of 2,6,9-trisubstituted purines, characterized by the presence of a common alkynyl substituent at C-2 and a range of different anilino/benzylamino groups at C-6, were synthesized. These compounds were evaluated for their capacity to inhibit c