26817-00-5

Usage

Uses

Used in Pharmaceutical Synthesis:
1-Hydroxy-1-methyl-3-phenylurea is used as a key intermediate in the synthesis of pharmaceuticals, particularly for the production of drugs with diuretic and antihypertensive properties. Its unique structure allows it to be a building block in the creation of various organic compounds, contributing to the development of novel therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-hydroxy-1-methyl-3-phenylurea has been studied for its potential biological activities. Its exploration in research has shown promise in various areas, indicating its potential as a precursor for the discovery of new drugs and therapeutic agents.
Used in Organic Compound Synthesis:
Beyond its pharmaceutical applications, 1-hydroxy-1-methyl-3-phenylurea is also utilized as a building block in the synthesis of a variety of other organic compounds. Its structural components make it a valuable asset in the development of new chemical entities with diverse applications across different industries.

InChI:InChI=1/C8H10N2O2/c1-10(12)8(11)9-7-5-3-2-4-6-7/h2-6,12H,1H3,(H,9,11)

Upstream product

• 593-77-1 N-Methylhydroxylamine 
• 103-71-9 phenyl isocyanate 
• 26843-94-7 C₆H₁₄N₂O₂ 

Downstream Products

• 92852-65-8 N-Methyl-N,O-bis-anilinoformyl-hydroxylamin 
• 593-77-1 N-Methylhydroxylamine 
• 463-79-6 carbonic-acid 
• 603-54-3 N,N-diphenylurea 
• 62-53-3 aniline 
• 5102-26-1 2-methyl-4-phenyl-[1,2,4]oxadiazolidine-3,5-dithione 
• 5181-21-5 2-methyl-4-phenyl-5-thioxo-[1,2,4]oxadiazolidin-3-one 
• 30574-83-5 C₁₂H₁₉N₂O₄PS 
• 30645-29-5 C₁₂H₂₁N₄O₃P 
• 31143-73-4 C₁₀H₁₅N₂O₄PS 
• 1500-32-9 2-Methyl-4-phenyl-1,2,4-oxadiazolidin-3,5-dione 
• 37931-96-7 N-Hydroxy-N-methyl-N'-(4-bromphenyl)-harnstoff 

Relevant academic research and scientific papers

Analogues of N-hydroxy-N′-phenylthiourea and N-hydroxy-N′-phenylurea as inhibitors of tyrosinase and melanin formation

A series of N-hydroxy-N′-phenylthiourea and N-hydroxy-N′-phenylurea analogues were prepared and evaluated as inhibitors of tyrosinase and melanin formation. The most active analogue 1 inhibited mushroom tyrosinase with an IC50 of around 0.29 μM

Method of inhibiting leukotriene biosynthesis

A method of inhibiting leukotriene biosynthesis, involving administering a compound of the formula: STR1 wherein M, R, R', R", and n are as defined herein. Also, a pharmaceutical composition involving such a compound and the use of such compounds in the manufacture of a pharmaceutical composition for inhibiting leukotriene biosynthesis.